Immunogenicity 4695

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
GRID2IP
Transcript ID
NM_001145118
HLA INFO
DQA*02:01 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*02:01 DQB*02:02
sequence
Full length protein sequence (1211 aa)
MATTA
1
TPATN
6
QGWPE
11
DFGFR
16
LGGSG
21
PCFVL
26
EVAKG
31
SSAHA
36
GGLRP
41
GDQIL
46
EVEGL
51
AVGGL
56
SRERL
61
VRLAR
66
RCPRV
71
PPSLG
76
VLPAP
81
DGGPG
86
PGSGP
91
AAPTT
96
VLRAP
101
RCGRG
106
LALGR
111
ELLRL
116
AGRKR
121
PDAVH
126
RERRR
131
KAQEF
136
SRKVD
141
EILGD
146
QPTAK
151
EQVFA
156
ALKQF
161
AAEQR
166
VDDLV
171
WTLTL
176
ALPRE
181
ACGPL
186
LDNLR
191
IFIPK
196
KHRAR
201
FDEVV
206
SQGLL
211
GKLCR
216
ARRAQ
221
GAQRL
226
RRSRS
231
EERPE
236
RLLVS
241
TRASA
246
PPRRP
251
DEPPP
256
RRASL
261
LVGGL
266
AGPGG
271
ARRTV
276
RVYKG
281
NKSFG
286
FTLRG
291
HGPVW
296
IESVL
301
PGSPA
306
DNAAL
311
KSGDR
316
ILFLN
321
GLDMR
326
NCSHD
331
KVVSM
336
LQGSG
341
AMPTL
346
VVEEG
351
LVPFA
356
SDSDS
361
LDSPN
366
PSSAL
371
TSLQW
376
VAEIL
381
PSSIR
386
VQGRT
391
FSQQL
396
EHLLT
401
PPERY
406
GVCRA
411
LESFF
416
QHRNI
421
DTLIV
426
DVYPV
431
LDTPA
436
KQVLW
441
QFIYQ
446
LLTYE
451
EQELC
456
QEKIA
461
CFLGY
466
TAMTA
471
EPEPE
476
LDLES
481
EPTPE
486
PQPRS
491
SLRAS
496
SMCRR
501
SLRSQ
506
GLEAG
511
LSCGP
516
SECPE
521
MPLPL
526
IPGER
531
QAGDG
536
TSLPE
541
TPNPK
546
MMSAV
551
YAELE
556
SRLNS
561
SFKGK
566
MGTVS
571
KSRAS
576
PPGPS
581
PAVTT
586
GPRTL
591
SGVSW
596
PSERL
601
LPSPC
606
YHPLC
611
SGGLA
616
SPSSS
621
ESHPY
626
ASLDS
631
SRAPS
636
PQPGP
641
GPICP
646
DSPPS
651
PDPTR
656
PPSRR
661
KLFTF
666
SHPVR
671
SRDTD
676
RFLDV
681
LSEQL
686
GPRVT
691
IVDDF
696
LTPEN
701
DYEEM
706
SFHDD
711
QGSFV
716
TNERS
721
SASDC
726
ISSSE
731
EGSSL
736
TYSSI
741
SDHIP
746
PPPLS
751
PPPPP
756
PLPFH
761
DAKPS
766
SRSSD
771
GSRGP
776
AQALA
781
KPLTQ
786
LSHPV
791
PPPPP
796
PPLPP
801
PVPCA
806
PPMLS
811
RGLGH
816
RRSET
821
SHMSV
826
KRLRW
831
EQVEN
836
SEGTI
841
WGQLG
846
EDSDY
851
DKLSD
856
MVKYL
861
DLELH
866
FGTQK
871
PAKPV
876
PGPEP
881
FRKKE
886
VVEIL
891
SHKKA
896
YNTSI
901
LLAHL
906
KLSPA
911
ELRQV
916
LMSME
921
PRRLE
926
PAHLA
931
QLLLF
936
APDAD
941
EEQRY
946
QAFRE
951
APGRL
956
SEPDQ
961
FVLQM
966
LSVPE
971
YKTRL
976
RSLHF
981
QATLQ
986
EKTEE
991
IRGSL
996
ECLRQ
1001
ASLEL
1006
KNSRK
1011
LAKIL
1016
EFVLA
1021
MGNYL
1026
NDGQP
1031
KTNKT
1036
TGFKI
1041
NFLTE
1046
LNSTK
1051
TVDGK
1056
STFLH
1061
ILAKS
1066
LSQHF
1071
PELLG
1076
FAQDL
1081
PTVPL
1086
AAKVN
1091
QRALT
1096
SDLAD
1101
LHGTI
1106
SEIQD
1111
ACQSI
1116
SPSSE
1121
DKFAM
1126
VMSSF
1131
LETAQ
1136
PALRA
1141
LDGLQ
1146
REAME
1151
ELGKA
1156
LAFFG
1161
EDSKA
1166
TTSEA
1171
FFGIF
1176
AEFMS
1181
KFERA
1186
LSDLQ
1191
AGEGL
1196
RSSGM
1201
VSPLA
1206
W
1211
Mutation Information
DNA mutation:
None
Peptide Range:
12 ~ 36
Mut AA position:
24 (13 in Wild Type peptide)
Alignment
Wild Type:
"GWPEDFGFRLGGSGPCFVLEVAKGS
||||||||||||.||||||||||||
Mutant:
GWPEDFGFRLGGCGPCFVLEVAKGS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) GRID2IP

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay