Immunogenicity 470

summary
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
PRKCG
Transcript ID
None
HLA INFO
A*03:01
TCR INFO

No TCR info found!

T cell Tumor cell A*03:01
sequence
Full length protein sequence (710 aa)
MAGLG
1
PGVGD
6
SEGGP
11
RPLFC
16
RKGAL
21
RQKVV
26
HEVKS
31
HKFTA
36
RFFKQ
41
PTFCS
46
HCTDF
51
IWGIG
56
KQGLQ
61
CQVCS
66
FVVHR
71
RCHEF
76
VTFEC
81
PGAGK
86
GPQTD
91
DPRNK
96
HKFRL
101
HSYSS
106
PTFCD
111
HCGSL
116
LYGLV
121
HQGMK
126
CSCCE
131
MNVHR
136
RCVRS
141
VPSLC
146
GVDHT
151
ERRGR
156
LQLEI
161
RAPTA
166
DEIHV
171
TVGEA
176
RNLIP
181
MDPNG
186
LSDPY
191
VKLKL
196
IPDPR
201
NLTKQ
206
KTRTV
211
KATLN
216
PVWNE
221
TFVFN
226
LKPGD
231
VERRL
236
SVEVW
241
DWDRT
246
SRNDF
251
MGAMS
256
FGVSE
261
LLKAP
266
VDGWY
271
KLLNQ
276
EEGEY
281
YNVPV
286
ADADN
291
CSLLQ
296
KFEAC
301
NYPLE
306
LYERV
311
RMGPS
316
SSPIP
321
SPSPS
326
PTDPK
331
RCFFG
336
ASPGR
341
LHISD
346
FSFLM
351
VLGKG
356
SFGKV
361
MLAER
366
RGSDE
371
LYAIK
376
ILKKD
381
VIVQD
386
DDVDC
391
TLVEK
396
RVLAL
401
GGRGP
406
GGRPH
411
FLTQL
416
HSTFQ
421
TPDRL
426
YFVME
431
YVTGG
436
DLMYH
441
IQQLG
446
KFKEP
451
HAAFY
456
AAEIA
461
IGLFF
466
LHNQG
471
IIYRD
476
LKLDN
481
VMLDA
486
EGHIK
491
ITDFG
496
MCKEN
501
VFPGT
506
TTRTF
511
CGTPD
516
YIAPE
521
IIAYQ
526
PYGKS
531
VDWWS
536
FGVLL
541
YEMLA
546
GQPPF
551
DGEDE
556
EELFQ
561
AIMEQ
566
TVTYP
571
KSLSR
576
EAVAI
581
CKGFL
586
TKHPG
591
KRLGS
596
GPDGE
601
PTIRA
606
HGFFR
611
WIDWE
616
RLERL
621
EIPPP
626
FRPRP
631
CGRSG
636
ENFDK
641
FFTRA
646
APALT
651
PPDRL
656
VLASI
661
DQADF
666
QGFTY
671
VNPDF
676
VHPDA
681
RSPTS
686
PVPVP
691
VISCT
696
PAFQL
701
CPRGF
706
Mutation Information
DNA mutation:
None
Peptide Range:
525 ~ 547
Mut AA position:
525 (1 in Wild Type peptide)
Alignment
Wild Type:
"----------EIIAYQPYGK---
.|||||||||
Mutant:
FCGTPDYIAPKIIAYQPYGKSVD"
reference

Nature, 2017

An immunogenic personal neoantigen vaccine for patients with melanoma

Gene Name (from Reference) PRKCG

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

peptide

T-cell Source

PBMCs

APC Type

autologous APCs

Assay

IFNg ELISPOT assay