Immunogenicity 4705

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
SLC44A5
Transcript ID
NM_152697
HLA INFO
B*07:02
TCR INFO

No TCR info found!

T cell Tumor cell B*07:02
sequence
Full length protein sequence (719 aa)
MNDTE
1
KPADT
6
PSEEE
11
DFGDP
16
RTYDP
21
DFKGP
26
VANRS
31
CTDVL
36
CCMIF
41
LLCII
46
GYIVL
51
GLVAW
56
VHGDP
61
RRAAY
66
PTDSQ
71
GHFCG
76
QKGTP
81
NENKT
86
ILFYF
91
NLLRC
96
TSPSV
101
LLNLQ
106
CPTTQ
111
ICVSK
116
CPEKF
121
LTYVE
126
MQLLY
131
TKDKS
136
YWEDY
141
RQFCK
146
TTAKP
151
VKSLT
156
QLLLD
161
DDCPT
166
AIFPS
171
KPFLQ
176
RCFPD
181
FSTKN
186
GTLTI
191
GSKMM
196
FQDGN
201
GGTRS
206
VVELG
211
IAANG
216
INKLL
221
DAKSL
226
GLKVF
231
EDYAR
236
TWYWI
241
LIGLT
246
IAMVL
251
SWIFL
256
ILLRF
261
IAGCL
266
FWVFM
271
IGVIG
276
IIGYG
281
IWHCY
286
QQYTN
291
LQERP
296
SSVLT
301
IYDIG
306
IQTNI
311
SMYFE
316
LQQTW
321
FTFMI
326
ILCII
331
EVIVI
336
LMLIF
341
LRNRI
346
RVAII
351
LLKEG
356
SKAIG
361
YVPST
366
LVYPA
371
LTFIL
376
LSICI
381
CYWVV
386
TAVFL
391
ATSGV
396
PVYKV
401
IAPGG
406
HCIHE
411
NQTCD
416
PEIFN
421
TTEIA
426
KACPG
431
ALCNF
436
AFYGG
441
KSLYH
446
QYIPT
451
FHVYN
456
LFVFL
461
WLINF
466
VIALG
471
QCALA
476
GAFAT
481
YYWAM
486
KKPDD
491
IPRYP
496
LFTAF
501
GRAIR
506
YHTGS
511
LAFGS
516
LIIAL
521
IQMFK
526
IVLEY
531
LDHRL
536
KRTQN
541
TLSKF
546
LQCCL
551
RCCFW
556
CLENA
561
IKFLN
566
RNAYI
571
MIAIY
576
GRNFC
581
RSAKD
586
AFNLL
591
MRNVL
596
KVAVT
601
DEVTY
606
FVLFL
611
GKLLV
616
AGSIG
621
VLAFL
626
FFTQR
631
LPVIA
636
QGPAS
641
LNYYW
646
VPLLT
651
VIFGS
656
YLIAH
661
GFFSV
666
YAMCV
671
ETIFI
676
CFCED
681
LERND
686
GSTEK
691
PYFVT
696
PNLHG
701
ILIKK
706
QLVPQ
711
KQKE
716
Mutation Information
DNA mutation:
None
Peptide Range:
93 ~ 117
Mut AA position:
105 (13 in Wild Type peptide)
Alignment
Wild Type:
"FYFNLLRCTSPSVLLNLQCPTTQIC
||||||||||||.||||||||||||
Mutant:
FYFNLLRCTSPSMLLNLQCPTTQIC"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SLC44A5

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay