Immunogenicity 472

summary
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
TBX4
Transcript ID
None
HLA INFO
B*41:02
TCR INFO

No TCR info found!

T cell Tumor cell B*41:02
sequence
Full length protein sequence (545 aa)
MLQDK
1
GLSES
6
EEAFR
11
APGPA
16
LGEAS
21
AANAP
26
EPALA
31
APGLS
36
GAALG
41
SPPGP
46
GADVV
51
AAAAA
56
EQTIE
61
NIKVG
66
LHEKE
71
LWKKF
76
HEAGT
81
EMIIT
86
KAGRR
91
MFPSY
96
KVKVT
101
GMNPK
106
TKYIL
111
LIDIV
116
PADDH
121
RYKFC
126
DNKWM
131
VAGKA
136
EPAMP
141
GRLYV
146
HPDSP
151
ATGAH
156
WMRQL
161
VSFQK
166
LKLTN
171
NHLDP
176
FGHII
181
LNSMH
186
KYQPR
191
LHIVK
196
ADENN
201
AFGSK
206
NTAFC
211
THVFP
216
ETSFI
221
SVTSY
226
QNHKI
231
TQLKI
236
ENNPF
241
AKGFR
246
GSDDS
251
DLRVA
256
RLQSK
261
EYPVI
266
SKSIM
271
RQRLI
276
SPQLS
281
ATPDV
286
GPLLG
291
THQAL
296
QHYQH
301
ENGAH
306
SQLAE
311
PQDLP
316
LSTFP
321
TQRDS
326
SLFYH
331
CLKRR
336
DGTRH
341
LDLPC
346
KRSYL
351
EAPSS
356
VGEDH
361
YFRSP
366
PPYDQ
371
QMLSP
376
SYCSE
381
VTPRE
386
ACMYS
391
GSGPE
396
IAGVS
401
GVDDL
406
PPPPL
411
SCNMW
416
TSVSP
421
YTSYS
426
VQTME
431
TVPYQ
436
PFPTH
441
FTATT
446
MMPRL
451
PTLSA
456
QSSQP
461
PGNAH
466
FSVYN
471
QLSQS
476
QVRER
481
GPSAS
486
FPRER
491
GLPQG
496
CERKP
501
PSPHL
506
NAANE
511
FLYSQ
516
TFSLS
521
RESSL
526
QYHSG
531
MGTVE
536
NWTDG
541
Mutation Information
DNA mutation:
None
Peptide Range:
265 ~ 289
Mut AA position:
271 (7 in Wild Type peptide)
Alignment
Wild Type:
"-----KEYPVISKSI----------
||||||.|||
Mutant:
ARLQSKEYPVIFKSIMRQRLISPQL"
reference

Nature, 2017

An immunogenic personal neoantigen vaccine for patients with melanoma

Gene Name (from Reference) TBX4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

None

T-cell Source

PBMCs

APC Type

autologous APCs

Assay

IFNg ELISPOT assay