Immunogenicity 475

summary
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
VPS16
Transcript ID
None
HLA INFO
A*03:01
TCR INFO

No TCR info found!

T cell Tumor cell A*03:01
sequence
Full length protein sequence (839 aa)
MDCYT
1
ANWNP
6
LGDSA
11
FYRKY
16
ELYSM
21
DWDLK
26
EELRD
31
CLVAA
36
APYGG
41
PIALL
46
RNPWR
51
KEKAA
56
SVRPV
61
LDIYS
66
ASGMP
71
LASLL
76
WKSGP
81
VVSLG
86
WSAEE
91
ELLCV
96
QEDGA
101
VLVYG
106
LHGDF
111
RRHFS
116
MGNEV
121
LQNRV
126
LDARI
131
FHTEF
136
GSGVA
141
ILTGA
146
HRFTL
151
SANVG
156
DLKLR
161
RMPEV
166
PGLQS
171
APSCW
176
TVLCQ
181
DRVAH
186
ILLAV
191
GPDLY
196
LLDHA
201
ACSAV
206
TPPGL
211
APGVS
216
SFLQM
221
AVSFT
226
YRHLA
231
LFTDT
236
GYIWM
241
GTASL
246
KEKLC
251
EFNCN
256
IRAPP
261
KQMVW
266
CSRPR
271
SKERA
276
VVVAW
281
ERRLM
286
VVGDA
291
PESIQ
296
FVLDE
301
DSYLV
306
PELDG
311
VRIFS
316
RSTHE
321
FLHEV
326
PAASE
331
EIFKI
336
ASMAP
341
GALLL
346
EAQKE
351
YEKES
356
QKADE
361
YLREI
366
QELGQ
371
LTQAV
376
QQCIE
381
AAGHE
386
HQPDM
391
QKSLL
396
RAASF
401
GKCFL
406
DRFPP
411
DSFVH
416
MCQDL
421
RVLNA
426
VRDYH
431
IGIPL
436
TYSQY
441
KQLTI
446
QVLLD
451
RLVLR
456
RLYPL
461
AIQIC
466
EYLRL
471
PEVQG
476
VSRIL
481
AHWAC
486
YKVQQ
491
KDVSD
496
EDVAR
501
AINQK
506
LGDTP
511
GVSYS
516
DIAAR
521
AYGCG
526
RTELA
531
IKLLE
536
YEPRS
541
GEQVP
546
LLLKM
551
KRSKL
556
ALSKA
561
IESGD
566
TDLVF
571
TVLLH
576
LKNEL
581
NRGDF
586
FMTLR
591
NQPMA
596
LSLYR
601
QFCKH
606
QELET
611
LKDLY
616
NQDDN
621
HQELG
626
SFHIR
631
ASYAA
636
EERIE
641
GRVAA
646
LQTAA
651
DAFYK
656
AKNEF
661
AAKAT
666
EDQMR
671
LLRLQ
676
RRLED
681
ELGGQ
686
FLDLS
691
LHDTV
696
TTLIL
701
GGHNK
706
RAEQL
711
ARDFR
716
IPDKR
721
LWWLK
726
LTALA
731
DLEDW
736
EELEK
741
FSKSK
746
KSPIG
751
YLPFV
756
EICMK
761
QHNKY
766
EAKKY
771
ASRVG
776
PEQKV
781
KALLL
786
VGDVA
791
QAADV
796
AIEHR
801
NEAEL
806
SLVLS
811
HCTGA
816
TDGAT
821
ADKIQ
826
RARAQ
831
AQKK
836
Mutation Information
DNA mutation:
None
Peptide Range:
398 ~ 422
Mut AA position:
404 (7 in Wild Type peptide)
Alignment
Wild Type:
"----------SLLRAASFGK-----
||||||.|||
Mutant:
GHEHQPDMQKSLLRAAFFGKCFLDR"
reference

Nature, 2017

An immunogenic personal neoantigen vaccine for patients with melanoma

Gene Name (from Reference) VPS16

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

peptide

T-cell Source

PBMCs

APC Type

autologous APCs

Assay

IFNg ELISPOT assay