Immunogenicity 4756

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
AMER3
Transcript ID
NM_152698
HLA INFO
C*05:01
TCR INFO

No TCR info found!

T cell Tumor cell C*05:01
sequence
Full length protein sequence (861 aa)
MELKR
1
GKTFI
6
KSSLQ
11
VSHEK
16
PPDPA
21
AVAAA
26
REGTG
31
PWSVL
36
PGGQQ
41
RPHSE
46
KGPQA
51
SPSAQ
56
EYDRC
61
PNKGA
66
QLDPK
71
GGPAA
76
LCGAT
81
FKPVR
86
KCKTH
91
DSMSG
96
AGRAT
101
AATGQ
106
LVGSA
111
SFPGS
116
PGSRR
121
MIDYR
126
HFVPQ
131
MPFVP
136
AVAKS
141
IPRKR
146
ISLKR
151
PKKCF
156
RNLFH
161
IRRNK
166
TEDLA
171
SLAAE
176
GKSLP
181
SPGDP
186
SDPGG
191
RRSKA
196
FLPPG
201
EGPGL
206
DGLCQ
211
DLLDS
216
ELLAD
221
ASFGL
226
CRALC
231
EDVAS
236
LQSFD
241
SLTGC
246
GEVFA
251
DESSV
256
PSLEL
261
NEGPE
266
SPTQA
271
AQGLE
276
SKVPR
281
GPLQG
286
SVEQL
291
ASPAQ
296
NEASD
301
FTRFW
306
DSVNR
311
SVRQQ
316
QRALL
321
GPWLS
326
GPQGT
331
DRDQS
336
RLDTA
341
GLAEL
346
PLCPC
351
RDPRS
356
GSKAS
361
SIDTG
366
TPKSE
371
QPESV
376
STSDE
381
GYYDS
386
FSPGL
391
EEDKK
396
EAESP
401
GTPAA
406
TFPRD
411
SYSGD
416
ALYEL
421
FHDPS
426
EGPLG
431
PSPDD
436
DLCVS
441
ESLSG
446
PALGT
451
PLSIC
456
SFRVG
461
AEENL
466
APAPG
471
PDLLS
476
QGFLQ
481
SSWKG
486
KECLL
491
KLCDT
496
ELAIT
501
MGIVS
506
WLRRG
511
PTPRA
516
PPTPG
521
QPAAP
526
PGSQG
531
APRAP
536
TEKLG
541
GREGL
546
ASDAG
551
GATVC
556
SAPSR
561
QELWA
566
HPGTT
571
GLLAG
576
ESKAL
581
GGATQ
586
GTGTL
591
SRDAS
596
REEET
601
RGHSE
606
GLFSS
611
MESAA
616
TSTTD
621
TSGKN
626
KAPVP
631
STWPC
636
SQKEP
641
GPPGV
646
LGCFR
651
GPWRP
656
GHGGD
661
TLDAE
666
PMLAG
671
CVARV
676
AALKI
681
SSNEQ
686
PPAAW
691
PPRQD
696
MGSGL
701
FGQRW
706
ARGPD
711
MLEQK
716
QSSSS
721
PSMTT
726
IHGLP
731
YSAST
736
QDQRC
741
RDRVQ
746
DLSWL
751
RVEPT
756
GLGVQ
761
AWASV
766
EDQPL
771
QLSTE
776
AVEQV
781
AHGSQ
786
LDSEP
791
RSAPA
796
ARWSS
801
QGHHP
806
ESLGL
811
TLNSQ
816
QEGGV
821
SASAP
826
ECRCS
831
LLARE
836
GLLCG
841
QPEVG
846
ASGPA
851
MAEPH
856
L
861
Mutation Information
DNA mutation:
None
Peptide Range:
196 ~ 220
Mut AA position:
208 (13 in Wild Type peptide)
Alignment
Wild Type:
"RRSKAFLPPGEGPGLDGLCQDLLDS
||||||||||||.||||||||||||
Mutant:
RRSKAFLPPGEGLGLDGLCQDLLDS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) AMER3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay