Immunogenicity 476

summary
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
MED24
Transcript ID
None
HLA INFO
B*35:01
TCR INFO

No TCR info found!

T cell Tumor cell B*35:01
sequence
Full length protein sequence (989 aa)
MKVVN
1
LKQAI
6
LQAWK
11
ERWSD
16
YQWAI
21
NMKKF
26
FPKGA
31
TWDIL
36
NLADA
41
LLEQA
46
MIGPS
51
PNPLI
56
LSYLK
61
YAISS
66
QMVSY
71
SSVLT
76
AISKF
81
DDFSR
86
DLCVQ
91
ALLDI
96
MDMFC
101
DRLSC
106
HGKAE
111
ECIGL
116
CRALL
121
SALHW
126
LLRCT
131
AASAE
136
RLREG
141
LEAGT
146
PAAGE
151
KQLAM
156
CLQRL
161
EKTLS
166
STKNR
171
ALLHI
176
AKLEE
181
ASSWT
186
AIEHS
191
LLKLG
196
EILAN
201
LSNPQ
206
LRSQA
211
EQCGT
216
LIRSI
221
PTMLS
226
VHAEQ
231
MHKTG
236
FPTVH
241
AVILL
246
EGTMN
251
LTGET
256
QSLVE
261
QLTMV
266
KRMQH
271
IPTPL
276
FVLEI
281
WKACF
286
VGLIE
291
SPEGT
296
EELKW
301
TAFTF
306
LKIPQ
311
VLVKL
316
KKYSH
321
GDKDF
326
TEDVN
331
CAFEF
336
LLKLT
341
PLLDK
346
ADQRC
351
NCDCT
356
NFLLQ
361
ECGKQ
366
GLLSE
371
ASVNN
376
LMAKR
381
KADRE
386
HAPQQ
391
KSGEN
396
ANIQP
401
NIQLI
406
LRAEP
411
TVTNI
416
LKTMD
421
ADHSK
426
SPEGL
431
LGVLG
436
HMLSG
441
KSLDL
446
LLAAA
451
AATGK
456
LKSFA
461
RKFIN
466
LNEFT
471
TYGSE
476
ESTKP
481
ASVRA
486
LLFDI
491
SFLML
496
CHVAQ
501
TYGSE
506
VILSE
511
SRTGA
516
EVPFF
521
ETWMQ
526
TCMPE
531
EGKIL
536
NPDHP
541
CFRPD
546
STKVE
551
SLVAL
556
LNNSS
561
EMKLV
566
QMKWH
571
EACLS
576
ISAAI
581
LEILN
586
AWENG
591
VLAFE
596
SIQKI
601
TDNIK
606
GKVCS
611
LAVCA
616
VAWLV
621
AHVRM
626
LGLDE
631
REKSL
636
QMIRQ
641
LAGPL
646
FSENT
651
LQFYN
656
ERVVI
661
MNSIL
666
ERMCA
671
DVLQQ
676
TATQI
681
KFPST
686
GVDTM
691
PYWNL
696
LPPKR
701
PIKEV
706
LTDIF
711
AKVLE
716
KGWVD
721
SRSIH
726
IFDTL
731
LHMGG
736
VYWFC
741
NNLIK
746
ELLKE
751
TRKEH
756
TLRAV
761
ELLYS
766
IFCLD
771
MQQVT
776
LVLLG
781
HILPG
786
LLTDS
791
SKWHS
796
LMDPP
801
GTALA
806
KLAVW
811
CALSS
816
YSSHK
821
GQAST
826
RQKKR
831
HREDI
836
EDYIS
841
LFPLD
846
DVQPS
851
KLMRL
856
LSSNE
861
DDANI
866
LSSPT
871
DRSMS
876
SSLSA
881
SQLHT
886
VNMRD
891
PLNRV
896
LANLF
901
LLISS
906
ILGSR
911
TAGPH
916
TQFVQ
921
WFMEE
926
CVDCL
931
EQGGR
936
GSVLQ
941
FMPFT
946
TVSEL
951
VKVSA
956
MSSPK
961
VVLAI
966
TDLSL
971
PLGRQ
976
VAAKA
981
IAAL
986
Mutation Information
DNA mutation:
None
Peptide Range:
947 ~ 972
Mut AA position:
None (None in Wild Type peptide)
Alignment
Wild Type:
"------MPFTTVSELV----------
|||||||||.
Mutant:
GSVLQFMPFTTVSELMKVSAMSSPKV"
reference

Nature, 2017

An immunogenic personal neoantigen vaccine for patients with melanoma

Gene Name (from Reference) MED24

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

None

T-cell Source

PBMCs

APC Type

autologous APCs

Assay

IFNg ELISPOT assay