Immunogenicity 478
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
RUSC2
Transcript ID
None
HLA INFO
B*15:01
TCR INFO
No TCR info found!
Full length protein sequence (1516 aa)
MDSPP
1
KLTGE
6
TLIVH
11
HIPLV
16
HCQVP
21
DRQCC
26
GGAGG
31
GGGST
36
RPNPF
41
CPPEL
46
GITQP
51
DQDLG
56
QADSL
61
LFSSL
66
HSAPG
71
GTARS
76
IDSTK
81
SRSRD
86
GRGPG
91
APKRH
96
NPFLL
101
QEGVG
106
EPGLG
111
DLYDD
116
SIGDS
121
ATQQS
126
FHLHG
131
TGQPN
136
FHLSS
141
FQLPP
146
SGPRV
151
GRPWG
156
TTRSR
161
AGVVE
166
GQEQE
171
PVMTL
176
DTQQC
181
GTSHC
186
CRPEL
191
EAETM
196
ELDEC
201
GGPGG
206
SGSGG
211
GASDT
216
SGFSF
221
DQEWK
226
LSSDE
231
SPRNP
236
GCSGS
241
GDQHC
246
RCSST
251
SSQSE
256
AADQS
261
MGYVS
266
DSSCN
271
SSDGV
276
LVTFS
281
TLYNK
286
MHGTP
291
RANLN
296
SAPQS
301
CSDSS
306
FCSHS
311
DPGAF
316
YLDLQ
321
PSPFE
326
SKMSY
331
ESHHP
336
ESGGR
341
EGGYG
346
CPHAS
351
SPELD
356
ANCNS
361
YRPHC
366
EPCPA
371
VADLT
376
ACFQS
381
QARLV
386
VATQN
391
YYKLV
396
TCDLS
401
SQSSP
406
SPAGS
411
SITSC
416
SEEHT
421
KISPP
426
PGPGP
431
DPGPS
436
QPSEY
441
YLFQK
446
PEVQP
451
EEQEA
456
VSSST
461
QAAAA
466
VGPTV
471
LEGQV
476
YTNTS
481
PPNLS
486
TGRQR
491
SRSYD
496
RSLQR
501
SPPVR
506
LGSLE
511
RMLSC
516
PVRLS
521
EGPAA
526
MAGPG
531
SPPRR
536
VTSFA
541
ELAKG
546
RKKTG
551
GSGSP
556
PLRVS
561
VGDSS
566
QEFSP
571
IQEAQ
576
QDRGA
581
PLDEG
586
TCCSH
591
SLPPM
596
PLGPG
601
MDLLG
606
PDPSP
611
PWSTQ
616
VCQGP
621
HSSEM
626
PPAGL
631
RATGQ
636
GPLAQ
641
LMDPG
646
PALPG
651
SPANS
656
HTQRD
661
ARARA
666
DGGGT
671
ESRPV
676
LRYSK
681
EQRPT
686
TLPIQ
691
PFVFQ
696
HHFPK
701
QLAKA
706
RALHS
711
LSQLY
716
SLSGC
721
SRTQQ
726
PAPLA
731
APAAQ
736
VSVPA
741
PSGEP
746
QASTP
751
RATGR
756
GARKA
761
GSEPE
766
TSRPS
771
PLGSY
776
SPIRS
781
VGPFG
786
PSTDS
791
SASTS
796
CSPPP
801
EQPTA
806
TESLP
811
PWSHS
816
CPSAV
821
RPATS
826
QQPQK
831
EDQKI
836
LTLTE
841
YRLHG
846
TGSLP
851
PLGSW
856
RSGLS
861
RAESL
866
ARGGG
871
EGSMA
876
TRPSN
881
ANHLS
886
PQALK
891
WREYR
896
RKNPL
901
GPPGL
906
SGSLD
911
RRSQE
916
ARLAR
921
RNPIF
926
EFPGS
931
LSAAS
936
HLNCR
941
LNGQA
946
VKPLP
951
LTCPD
956
FQDPF
961
SLTEK
966
PPAEF
971
CLSPD
976
GSSEA
981
ISIDL
986
LQKKG
991
LVKAV
996
NIAVD
1001
LIVAH
1006
FGTSR
1011
DPGVK
1016
AKLGN
1021
SSVSP
1026
NVGHL
1031
VLKYL
1036
CPAVR
1041
AVLED
1046
GLKAF
1051
VLDVI
1056
IGQRK
1061
NMPWS
1066
VVEAS
1071
TQLGP
1076
STKVL
1081
HGLYN
1086
KVSQF
1091
PELTS
1096
HTMRF
1101
NAFIL
1106
GLLNI
1111
RSLEF
1116
WFNHL
1121
YNHED
1126
IIQTH
1131
YQPWG
1136
FLSAA
1141
HTVCP
1146
GLFEE
1151
LLLLL
1156
QPLAL
1161
LPFSL
1166
DLLFQ
1171
HRLLQ
1176
SGQQQ
1181
RQHKE
1186
LLRVS
1191
QDLLL
1196
SAHST
1201
LQLAR
1206
ARGQE
1211
GPGDV
1216
DRAAQ
1221
GERVK
1226
GVGAS
1231
EGGEE
1236
EEEEE
1241
ETEEV
1246
AEAAG
1251
GSGRA
1256
RWARG
1261
GQAGW
1266
WYQLM
1271
QSSQV
1276
YIDGS
1281
IEGSR
1286
FPRGS
1291
SNSSS
1296
EKKKG
1301
AGGGG
1306
PPQAP
1311
PPREG
1316
VVEGA
1321
EACPA
1326
SEEAL
1331
GRERG
1336
WPFWM
1341
GSPPD
1346
SVLAE
1351
LRRSR
1356
EREGP
1361
AASPA
1366
ENEEG
1371
ASEPS
1376
PGGIK
1381
WGHLF
1386
GSRKA
1391
QREAR
1396
PTNRL
1401
PSDWL
1406
SLDKS
1411
MFQLV
1416
AQTVG
1421
SRREP
1426
EPKES
1431
LQEPH
1436
SPALP
1441
SSPPC
1446
EVQAL
1451
CHHLA
1456
TGPGQ
1461
LSFHK
1466
GDILR
1471
VLGRA
1476
GGDWL
1481
RCSRG
1486
PDSGL
1491
VPLAY
1496
VTLTP
1501
TPSPT
1506
PGSSQ
1511
N
1516
Mutation Information
DNA mutation:
None
Peptide Range:
564 ~ 589
Mut AA position:
569 (6 in Wild Type peptide)
Alignment
Wild Type:
"-------VSVGDSSQEF---------
|||||.||||
Mutant:
SGSPPLRVSVGDFSQEFSPIQEAQQD"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) RUSC2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
None
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay