Immunogenicity 4783

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
PRB2
Transcript ID
NM_006248
HLA INFO
C*03:04
TCR INFO

No TCR info found!

T cell Tumor cell C*03:04
sequence
Full length protein sequence (416 aa)
MLLIL
1
LSVAL
6
LALSS
11
AQNLN
16
EDVSQ
21
EESPS
26
LIAGN
31
PQGAP
36
PQGGN
41
KPQGP
46
PSPPG
51
KPQGP
56
PPQGG
61
NQPQG
66
PPPPP
71
GKPQG
76
PPPQG
81
GNKPQ
86
GPPPP
91
GKPQG
96
PPPQG
101
DKSRS
106
PRSPP
111
GKPQG
116
PPPQG
121
GNQPQ
126
GPPPP
131
PGKPQ
136
GPPPQ
141
GGNKP
146
QGPPP
151
PGKPQ
156
GPPPQ
161
GDNKS
166
RSSRS
171
PPGKP
176
QGPPP
181
QGGNQ
186
PQGPP
191
PPPGK
196
PQGPP
201
PQGGN
206
KPQGP
211
PPPGK
216
PQGPP
221
PQGDN
226
KSQSA
231
RSPPG
236
KPQGP
241
PPQGG
246
NQPQG
251
PPPPP
256
GKPQG
261
PPPQG
266
GNKPQ
271
GPPPP
276
GKPQG
281
PPPQG
286
GSKSR
291
SSRSP
296
PGKPQ
301
GPPPQ
306
GGNQP
311
QGPPP
316
PPGKP
321
QGPPP
326
QGGNK
331
PQGPP
336
PPGKP
341
QGPPP
346
QGGSK
351
SRSAR
356
SPPGK
361
PQGPP
366
QQEGN
371
NPQGP
376
PPPAG
381
GNPQQ
386
PQAPP
391
AGQPQ
396
GPPRP
401
PQGGR
406
PSRPP
411
Q
416
Mutation Information
DNA mutation:
None
Peptide Range:
302 ~ 326
Mut AA position:
314 (13 in Wild Type peptide)
Alignment
Wild Type:
"GKPQGPPPQGGNQPQGPPPPPGKPQ
||||||||||||.||||||||||||
Mutant:
GKPQGPPPQGGNKPQGPPPPPGKPQ"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PRB2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay