Immunogenicity 480

summary
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
ARHGEF15
Transcript ID
None
HLA INFO
B*15:01
TCR INFO

No TCR info found!

T cell Tumor cell B*15:01
sequence
Full length protein sequence (841 aa)
MSAQS
1
LPAAT
6
PPTQK
11
PPRII
16
RPRPP
21
SRSRA
26
AQSPG
31
PPHNG
36
SSPQE
41
LPRNS
46
NDAPT
51
PMCTP
56
IFWEP
61
PAASL
66
KPPAL
71
LPPSA
76
SRASL
81
DSQTS
86
PDSPS
91
STPTP
96
SPVSR
101
RSASP
106
EPAPR
111
SPVPP
116
PKPSG
121
SPCTP
126
LLPMA
131
GVLAQ
136
NGSAS
141
APGTV
146
RRLAG
151
RFEGG
156
AEGRA
161
QDADA
166
PEPGL
171
QARAD
176
VNGER
181
EAPLT
186
GSGSQ
191
ENGAP
196
DAGLA
201
CPPCC
206
PCVCH
211
TTRPG
216
LELRW
221
VPVGG
226
YEEVP
231
RVPRR
236
ASPLR
241
TSRSR
246
PHPPS
251
IGHPA
256
VVLTS
261
YRSTA
266
ERKLL
271
PLLKP
276
PKPTR
281
VRQDA
286
TIFGD
291
PPQPD
296
LDLLS
301
EDGIQ
306
TGDSP
311
DEAPQ
316
NTPPA
321
TVEGR
326
EEEGL
331
EVLKE
336
QNWEL
341
PLQDE
346
PLYQT
351
YRAAV
356
LSEEL
361
WGVGE
366
DGSPS
371
PANAG
376
DAPTF
381
PRPPG
386
PRNTL
391
WQELP
396
AVQAS
401
GLLDT
406
LSPQE
411
RRMQE
416
SLFEV
421
VTSEA
426
SYLRS
431
LRLLT
436
DTFVL
441
SQALR
446
DTLTP
451
RDHHT
456
LFSNV
461
QRVQG
466
VSERF
471
LATLL
476
SRVRS
481
SPHIS
486
DLCDV
491
VHAHA
496
VGPFS
501
VYVDY
506
VRNQQ
511
YQEET
516
YSRLM
521
DTNVR
526
FSAEL
531
RRLQS
536
LPKCE
541
RLPLP
546
SFLLL
551
PFQRI
556
TRLRM
561
LLQNI
566
LRQTE
571
EGSSR
576
QENAQ
581
KALGA
586
VSKII
591
ERCSA
596
EVGRM
601
KQTEE
606
LIRLT
611
QRLRF
616
HKVKA
621
LPLVS
626
WSRRL
631
EFQGE
636
LTELG
641
CRRGG
646
VLFAS
651
RPRFT
656
PLCLL
661
LFSDL
666
LLITQ
671
PKSGQ
676
RLQVL
681
DYAHR
686
SLVQA
691
QQVPD
696
PSGPP
701
TFRLS
706
LLSNH
711
QGRPT
716
HRLLQ
721
ASSLS
726
DMQRW
731
LGAFP
736
TPGPL
741
PCSPD
746
TIYED
751
CDCSQ
756
ELCSE
761
SSAPA
766
KTEGR
771
SLESR
776
AAPKH
781
LHKTP
786
EGWLK
791
GLPGA
796
FPAQL
801
VCEVT
806
GEHER
811
RRHLR
816
QNQRL
821
LEAVG
826
SSSGT
831
PNAPP
836
P
841
Mutation Information
DNA mutation:
None
Peptide Range:
651 ~ 666
Mut AA position:
651 (1 in Wild Type peptide)
Alignment
Wild Type:
"----VLFASRPRF---
.||||||||
Mutant:
RRGGALFASRPRFTPL"
reference

Nature, 2017

An immunogenic personal neoantigen vaccine for patients with melanoma

Gene Name (from Reference) ARHGEF15

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

None

T-cell Source

PBMCs

APC Type

autologous APCs

Assay

IFNg ELISPOT assay