Immunogenicity 481

summary
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
GTF3C2
Transcript ID
None
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (922 aa)
MYRGQ
1
PFWGV
6
LMDTC
11
GVGYV
16
ALGEA
21
GPVGN
26
MTVVD
31
SPGQE
36
VLNQL
41
DVKTS
46
SEMTS
51
AEASV
56
EMSLP
61
TPLPG
66
FEDSP
71
DQRRL
76
PPEQE
81
SLSRL
86
EQPDL
91
SSEMS
96
KVSKP
101
RASKP
106
GRKRG
111
GRTRK
116
GPKRP
121
QQPNP
126
PSAPL
131
VPGLL
136
DQSNP
141
LSTPM
146
PKKRG
151
RKSKA
156
ELLLL
161
KLSKD
166
LDRPE
171
SQSPK
176
RPPED
181
FETPS
186
GERPR
191
RRAAQ
196
VALLY
201
LQELA
206
EELST
211
ALPAP
216
VSCPE
221
GPKVS
226
SPTKP
231
KKIRQ
236
PAACP
241
GGEEV
246
DGAPR
251
DEDFF
256
LQVEA
261
EDVEE
266
SEGPS
271
ESSSE
276
PEPVV
281
PRSTP
286
RGSTS
291
GKQKP
296
HCRGM
301
APNGL
306
PNHIM
311
APVWK
316
CLHLT
321
KDFRE
326
QKHSY
331
WEFAE
336
WIPLA
341
WKWHL
346
LSELE
351
AAPYL
356
PQEEK
361
SPLFS
366
VQREG
371
LPEDG
376
TLYRI
381
NRFSS
386
ITAHP
391
ERWDV
396
SFFTG
401
GPLWA
406
LDWCP
411
VPEGA
416
GASQY
421
VALFS
426
SPDMN
431
ETHPL
436
SQLHS
441
GPGLL
446
QLWGL
451
GTLQQ
456
ESCPG
461
NRAHF
466
VYGIA
471
CDNGC
476
IWDLK
481
FCPSG
486
AWELP
491
GTPRK
496
APLLP
501
RLGLL
506
ALACS
511
DGKVL
516
LFSLP
521
HPEAL
526
LAQQP
531
PDAVK
536
PAIYK
541
VQCVA
546
TLQVG
551
SMQAT
556
DPSEC
561
GQCLS
566
LAWMP
571
TRPHQ
576
HLAAG
581
YYNGM
586
VVFWN
591
LPTNS
596
PLQRI
601
RLSDG
606
SLKLY
611
PFQCF
616
LAHDQ
621
AVRTL
626
QWCKA
631
NSHFL
636
VSAGS
641
DRKIK
646
FWDLR
651
RPYEP
656
INSIK
661
RFLST
666
ELAWL
671
LPYNG
676
VTVAQ
681
DNCYA
686
SYGLC
691
GIHYI
696
DAGYL
701
GFKAY
706
FTAPR
711
KGTVW
716
SLSGS
721
DWLGT
726
IAAGD
731
ISGEL
736
IAAIL
741
PDMAL
746
NPINV
751
KRPVE
756
RRFPI
761
YKADL
766
IPYQD
771
SPEGP
776
DHSSA
781
SSGVP
786
NPPKA
791
RTYTE
796
TVNHH
801
YLLFQ
806
DTDLG
811
SFHDL
816
LRREP
821
MLRMQ
826
EGEGH
831
SQLCL
836
DRLQL
841
EAIHK
846
VRFSP
851
NLDSY
856
GWLVS
861
GGQSG
866
LVRIH
871
FVRGL
876
ASPLG
881
HRMQL
886
ESRAH
891
FNAMF
896
QPSSP
901
TRRPG
906
FSPTS
911
HRLLP
916
TP
921
Mutation Information
DNA mutation:
None
Peptide Range:
806 ~ 829
Mut AA position:
811 (6 in Wild Type peptide)
Alignment
Wild Type:
"-------YLLFQDTDL--------
|||||.|||
Mutant:
TETVNHHYLLFQNTDLGSFHDLLR"
reference

Nature, 2017

An immunogenic personal neoantigen vaccine for patients with melanoma

Gene Name (from Reference) GTF3C2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

peptide

T-cell Source

PBMCs

APC Type

autologous APCs

Assay

IFNg ELISPOT assay