Immunogenicity 482
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
TBX10
Transcript ID
None
HLA INFO
A*01:03
TCR INFO
No TCR info found!
Full length protein sequence (385 aa)
MAAFL
1
SAGLG
6
ILAPS
11
ETYPL
16
PTTSS
21
GWEPR
26
LGSPF
31
PSGPC
36
TSSTG
41
AQAVA
46
EPTGQ
51
GPKNP
56
RVSRV
61
TVQLE
66
MKPLW
71
EEFNQ
76
LGTEM
81
IVTKA
86
GRRMF
91
PPFQV
96
KILGM
101
DSLAD
106
YALLM
111
DFIPL
116
DDKRY
121
RYAFH
126
SSAWL
131
VAGKA
136
DPATP
141
GRVHF
146
HPDSP
151
AKGAQ
156
WMRQI
161
VSFDK
166
LKLTN
171
NLLDD
176
NGHII
181
LNSMH
186
RYQPR
191
FHVVF
196
VDPRK
201
DSERY
206
AQENF
211
KSFIF
216
TETQF
221
TAVTA
226
YQNHR
231
ITQLK
236
IASNP
241
FAKGF
246
RESDL
251
DSWPV
256
APRPL
261
LSVPA
266
RSHSS
271
LSPCV
276
LKGAT
281
DREKD
286
PNKAS
291
ASTSK
296
TPAWL
301
HHQLL
306
PPPEV
311
LLAPA
316
TYRPV
321
TYQSL
326
YSGAP
331
SHLGI
336
PRTRP
341
APYPL
346
PNIRA
351
DRDQG
356
GLPLP
361
AGLGL
366
LSPTV
371
VCLGP
376
GQDSQ
381
Mutation Information
DNA mutation:
None
Peptide Range:
252 ~ 274
Mut AA position:
256 (5 in Wild Type peptide)
Alignment
Wild Type:
"------ESDLDSWPV--------
||||.||||
Mutant:
FAKGFRESDLNSWPVAPRPLLSV"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) TBX10
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay