Immunogenicity 4829
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
NAV2
Transcript ID
NM_001111018
HLA INFO
C*12:03
TCR INFO
No TCR info found!
Full length protein sequence (2365 aa)
MESVS
1
ESSQQ
6
QKRKP
11
VIHGL
16
EDQKR
21
IYTDW
26
ANHYL
31
AKSGH
36
KRLIR
41
DLQQD
46
VTDGV
51
LLAQI
56
IQVVA
61
NEKIE
66
DINGC
71
PKNRS
76
QMIEN
81
IDACL
86
NFLAA
91
KGINI
96
QGLSA
101
EEIRN
106
GNLKA
111
ILGLF
116
FSLSR
121
YKQQQ
126
QQPQK
131
QHLSS
136
PLPPA
141
VSQVA
146
GAPSQ
151
CQAGT
156
PQQQV
161
PVTPQ
166
APCQP
171
HQPAP
176
HQQSK
181
AQAEM
186
QSRLP
191
GPTAR
196
VSAAG
201
SEAKT
206
RGGST
211
TANNR
216
RSQSF
221
NNYDK
226
SKPVT
231
SPPPP
236
PSSHE
241
KEPLA
246
SSASS
251
HPGMS
256
DNAPA
261
SLESG
266
SSSTP
271
TNCST
276
SSAIP
281
QPGAA
286
TKPWR
291
SKSLS
296
VKHSA
301
TVSML
306
SVKPP
311
GPEAP
316
RPTPE
321
AMKPA
326
PNNQK
331
SMLEK
336
LKLFN
341
SKGGS
346
KAGEG
351
PGSRD
356
TSCER
361
LETLP
366
SFEES
371
EELEA
376
ASRML
381
TTVGP
386
ASSSP
391
KIALK
396
GIAQR
401
TFSRA
406
LTNKK
411
SSLKG
416
NEKEK
421
EKQQR
426
EKDKE
431
KSKDL
436
AKRAS
441
VTERL
446
DLKEE
451
PKEDP
456
SGAAV
461
PEMPK
466
KSSKI
471
ASFIP
476
KGGKL
481
NSAKK
486
EPMAP
491
SHSGI
496
PKPGM
501
KSMPG
506
KSPSA
511
PAPSK
516
EGERS
521
RSGKL
526
SSGLP
531
QQKPQ
536
LDGRH
541
SSSSS
546
SLASS
551
EGKGP
556
GGTTL
561
NHSIS
566
SQTVS
571
GSVGT
576
TQTTG
581
SNTVS
586
VQLPQ
591
PQQQY
596
NHPNT
601
ATVAP
606
FLYRS
611
QTDTE
616
GNVTA
621
ESSST
626
GVSVE
631
PSHFT
636
KTGQP
641
ALEEL
646
TGEDP
651
EARRL
656
RTVKN
661
IADLR
666
QNLEE
671
TMSSL
676
RGTQV
681
THSTL
686
ETTFD
691
TNVTT
696
EMSGR
701
SILSL
706
TGRPT
711
PLSWR
716
LGQSS
721
PRLQA
726
GDAPS
731
MGNGY
736
PPRAN
741
ASRFI
746
NTESG
751
RYVYS
756
APLRR
761
QLASR
766
GSSVC
771
HVDVS
776
DKAGD
781
EMDLE
786
GISMD
791
APGYM
796
SDGDV
801
LSKNI
806
RTDDI
811
TSGYM
816
TDGGL
821
GLYTR
826
RLNRL
831
PDGMA
836
VVRET
841
LQRNT
846
SLGLG
851
DADSW
856
DDSSS
861
VSSGI
866
SDTID
871
NLSTD
876
DINTS
881
SSISS
886
YANTP
891
ASSRK
896
NLDVQ
901
TDAEK
906
HSQVE
911
RNSLW
916
SGDDV
921
KKSDG
926
GSDSG
931
IKMEP
936
GSKWR
941
RNPSD
946
VSDES
951
DKSTS
956
GKKNP
961
VISQT
966
GSWRR
971
GMTAQ
976
VGITM
981
PRTKP
986
SAPAG
991
ALKTP
996
GTGKT
1001
DDAKV
1006
SEKGR
1011
LSPKA
1016
SQVKR
1021
SPSDA
1026
GRSSG
1031
DESKK
1036
PLPSS
1041
SRTPT
1046
ANANS
1051
FGFKK
1056
QSGSA
1061
AGLAM
1066
ITASG
1071
VTVTS
1076
RSATL
1081
GKIPK
1086
SSALV
1091
SRSAG
1096
RKSSM
1101
DGAQN
1106
QDDGY
1111
LALSS
1116
RTNLQ
1121
YRSLP
1126
RPSKS
1131
NSRNG
1136
AGNRS
1141
STSSI
1146
DSNIS
1151
SKSAG
1156
LPVPK
1161
LREPS
1166
KTALG
1171
SSLPG
1176
LVNQT
1181
DKEKG
1186
ISSDN
1191
ESVAS
1196
CNSVK
1201
VNPAA
1206
QPVSS
1211
PAQTS
1216
LQPGA
1221
KYPDV
1226
ASPTL
1231
RRLFG
1236
GKPTK
1241
QVPIA
1246
TAENM
1251
KNSVV
1256
ISNPH
1261
ATMTQ
1266
QGNLD
1271
SPSGS
1276
GVLSS
1281
GSSSP
1286
LYSKN
1291
VDLNQ
1296
SPLAS
1301
SPSSA
1306
HSAPS
1311
NSLTW
1316
GTNAS
1321
SSSAV
1326
SKDGL
1331
GFQSV
1336
SSLHT
1341
SCESI
1346
DISLS
1351
SGGVP
1356
SHNSS
1361
TGLIA
1366
SSKDD
1371
SLTPF
1376
VRTNS
1381
VKTTL
1386
SESPL
1391
SSPAA
1396
SPKFC
1401
RSTLP
1406
RKQDS
1411
DPHLD
1416
RNTLP
1421
KKGLR
1426
YTPTS
1431
QLRTQ
1436
EDAKE
1441
WLRSH
1446
SAGGL
1451
QDTAA
1456
NSPFS
1461
SGSSV
1466
TSPSG
1471
TRFNF
1476
SQLAS
1481
PTTVT
1486
QMSLS
1491
NPTML
1496
RTHSL
1501
SNADG
1506
QYDPY
1511
TDSRF
1516
RNSSM
1521
SLDEK
1526
SRTMS
1531
RSGSF
1536
RDGFE
1541
EVHGS
1546
SLSLV
1551
SSTSS
1556
VYSTP
1561
EEKCQ
1566
SEIRK
1571
LRREL
1576
DASQE
1581
KVSAL
1586
TTQLT
1591
ANAHL
1596
VAAFE
1601
QSLGN
1606
MTIRL
1611
QSLTM
1616
TAEQK
1621
DSELN
1626
ELRKT
1631
IELLK
1636
KQNAA
1641
AQAAI
1646
NGVIN
1651
TPELN
1656
CKGNG
1661
TAQSA
1666
DLRIR
1671
RQHSS
1676
DSVSS
1681
INSAT
1686
SHSSV
1691
GSNIE
1696
SDSKK
1701
KKRKN
1706
WLRSS
1711
FKQAF
1716
GKKKS
1721
PKSAS
1726
SHSDI
1731
EEMTD
1736
SSLPS
1741
SPKLP
1746
HNGST
1751
GSTPL
1756
LRNSH
1761
SNSLI
1766
SECMD
1771
SEAET
1776
VMQLR
1781
NELRD
1786
KEMKL
1791
TDIRL
1796
EALSS
1801
AHQLD
1806
QLREA
1811
MNRMQ
1816
SEIEK
1821
LKAEN
1826
DRLKS
1831
ESQGS
1836
GCSRA
1841
PSQVS
1846
ISASP
1851
RQSMG
1856
LSQHS
1861
LNLTE
1866
STSLD
1871
MLLDD
1876
TGECS
1881
ARKEG
1886
GRHVK
1891
IVVSF
1896
QEEMK
1901
WKEDS
1906
RPHLF
1911
LIGCI
1916
GVSGK
1921
TKWDV
1926
LDGVV
1931
RRLFK
1936
EYIIH
1941
VDPVS
1946
QLGLN
1951
SDSVL
1956
GYSIG
1961
EIKRS
1966
NTSET
1971
PELLP
1976
CGYLV
1981
GENTT
1986
ISVTV
1991
KGLAE
1996
NSLDS
2001
LVFES
2006
LIPKP
2011
ILQRY
2016
VSLLI
2021
EHRRI
2026
ILSGP
2031
SGTGK
2036
TYLAN
2041
RLSEY
2046
IVLRE
2051
GRELT
2056
DGVIA
2061
TFNVD
2066
HKSSK
2071
ELRQY
2076
LSNLA
2081
DQCNS
2086
ENNAV
2091
DMPLV
2096
IILDN
2101
LHHVS
2106
SLGEI
2111
FNGLL
2116
NCKYH
2121
KCPYI
2126
IGTMN
2131
QATSS
2136
TPNLQ
2141
LHHNF
2146
RWVLC
2151
ANHTE
2156
PVKGF
2161
LGRFL
2166
RRKLM
2171
ETEIS
2176
GRVRN
2181
MELVK
2186
IIDWI
2191
PKVWH
2196
HLNRF
2201
LEAHS
2206
SSDVT
2211
IGPRL
2216
FLSCP
2221
IDVDG
2226
SRVWF
2231
TDLWN
2236
YSIIP
2241
YLLEA
2246
VREGL
2251
QLYGR
2256
RAPWE
2261
DPAKW
2266
VMDTY
2271
PWAAS
2276
PQQHE
2281
WPPLL
2286
QLRPE
2291
DVGFD
2296
GYSMP
2301
REGST
2306
SKQMP
2311
PSDAE
2316
GDPLM
2321
NMLMR
2326
LQEAA
2331
NYSSP
2336
QSYDS
2341
DSNSN
2346
SHHDD
2351
ILDSS
2356
LESTL
2361
Mutation Information
DNA mutation:
None
Peptide Range:
1974 ~ 1998
Mut AA position:
1986 (13 in Wild Type peptide)
Alignment
Wild Type:
"ETPELLPCGYLVGENTTISVTVKGL
||||||||||||.||||||||||||
Mutant:
ETPELLPCGYLVEENTTISVTVKGL"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) NAV2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay