Immunogenicity 4838

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
TP53
Transcript ID
NM_001276761
HLA INFO
B*13:02
TCR INFO

No TCR info found!

T cell Tumor cell B*13:02
sequence
Full length protein sequence (354 aa)
MDDLM
1
LSPDD
6
IEQWF
11
TEDPG
16
PDEAP
21
RMPEA
26
APPVA
31
PAPAA
36
PTPAA
41
PAPAP
46
SWPLS
51
SSVPS
56
QKTYQ
61
GSYGF
66
RLGFL
71
HSGTA
76
KSVTC
81
TYSPA
86
LNKMF
91
CQLAK
96
TCPVQ
101
LWVDS
106
TPPPG
111
TRVRA
116
MAIYK
121
QSQHM
126
TEVVR
131
RCPHH
136
ERCSD
141
SDGLA
146
PPQHL
151
IRVEG
156
NLRVE
161
YLDDR
166
NTFRH
171
SVVVP
176
YEPPE
181
VGSDC
186
TTIHY
191
NYMCN
196
SSCMG
201
GMNRR
206
PILTI
211
ITLED
216
SSGNL
221
LGRNS
226
FEVRV
231
CACPG
236
RDRRT
241
EEENL
246
RKKGE
251
PHHEL
256
PPGST
261
KRALP
266
NNTSS
271
SPQPK
276
KKPLD
281
GEYFT
286
LQIRG
291
RERFE
296
MFREL
301
NEALE
306
LKDAQ
311
AGKEP
316
GGSRA
321
HSSHL
326
KSKKG
331
QSTSR
336
HKKLM
341
FKTEG
346
PDSD
351
Mutation Information
DNA mutation:
None
Peptide Range:
221 ~ 245
Mut AA position:
233 (13 in Wild Type peptide)
Alignment
Wild Type:
"SSGNLLGRNSFEVRVCACPGRDRRT
||||||||||||.||||||||||||
Mutant:
SSGNLLGRNSFEMRVCACPGRDRRT"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) TP53

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay