Immunogenicity 484
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
KMT2A
Transcript ID
None
HLA INFO
B*08:01
TCR INFO
No TCR info found!
Full length protein sequence (3972 aa)
MAHSC
1
RWRFP
6
ARPGT
11
TGGGG
16
GGGRR
21
GLGGA
26
PRQRV
31
PALLL
36
PPGPP
41
VGGGG
46
PGAPP
51
SPPAV
56
AAAAA
61
AAGSS
66
GAGVP
71
GGAAA
76
ASAAS
81
SSSAS
86
SSSSS
91
SSSAS
96
SGPAL
101
LRVGP
106
GFDAA
111
LQVSA
116
AIGTN
121
LRRFR
126
AVFGE
131
SGGGG
136
GSGED
141
EQFLG
146
FGSDE
151
EVRVR
156
SPTRS
161
PSVKT
166
SPRKP
171
RGRPR
176
SGSDR
181
NSAIL
186
SDPSV
191
FSPLN
196
KSETK
201
SGDKI
206
KKKDS
211
KSIEK
216
KRGRP
221
PTFPG
226
VKIKI
231
THGKD
236
ISELP
241
KGNKE
246
DSLKK
251
IKRTP
256
SATFQ
261
QATKI
266
KKLRA
271
GKLSP
276
LKSKF
281
KTGKL
286
QIGRK
291
GVQIV
296
RRRGR
301
PPSTE
306
RIKTP
311
SGLLI
316
NSELE
321
KPQKV
326
RKDKE
331
GTPPL
336
TKEDK
341
TVVRQ
346
SPRRI
351
KPVRI
356
IPSSK
361
RTDAT
366
IAKQL
371
LQRAK
376
KGAQK
381
KIEKE
386
AAQLQ
391
GRKVK
396
TQVKN
401
IRQFI
406
MPVVS
411
AISSR
416
IIKTP
421
RRFIE
426
DEDYD
431
PPIKI
436
ARLES
441
TPNSR
446
FSAPS
451
CGSSE
456
KSSAA
461
SQHSS
466
QMSSD
471
SSRSS
476
SPSVD
481
TSTDS
486
QASEE
491
IQVLP
496
EERSD
501
TPEVH
506
PPLPI
511
SQSPE
516
NESND
521
RRSRR
526
YSVSE
531
RSFGS
536
RTTKK
541
LSTLQ
546
SAPQQ
551
QTSSS
556
PPPPL
561
LTPPP
566
PLQPA
571
SSISD
576
HTPWL
581
MPPTI
586
PLASP
591
FLPAS
596
TAPMQ
601
GKRKS
606
ILREP
611
TFRWT
616
SLKHS
621
RSEPQ
626
YFSSA
631
KYAKE
636
GLIRK
641
PIFDN
646
FRPPP
651
LTPED
656
VGFAS
661
GFSAS
666
GTAAS
671
ARLFS
676
PLHSG
681
TRFDM
686
HKRSP
691
LLRAP
696
RFTPS
701
EAHSR
706
IFESV
711
TLPSN
716
RTSAG
721
TSSSG
726
VSNRK
731
RKRKV
736
FSPIR
741
SEPRS
746
PSHSM
751
RTRSG
756
RLSSS
761
ELSPL
766
TPPSS
771
VSSSL
776
SISVS
781
PLATS
786
ALNPT
791
FTFPS
796
HSLTQ
801
SGESA
806
EKNQR
811
PRKQT
816
SAPAE
821
PFSSS
826
SPTPL
831
FPWFT
836
PGSQT
841
ERGRN
846
KDKAP
851
EELSK
856
DRDAD
861
KSVEK
866
DKSRE
871
RDRER
876
EKENK
881
RESRK
886
EKRKK
891
GSEIQ
896
SSSAL
901
YPVGR
906
VSKEK
911
VVGED
916
VATSS
921
SAKKA
926
TGRKK
931
SSSHD
936
SGTDI
941
TSVTL
946
GDTTA
951
VKTKI
956
LIKKG
961
RGNLE
966
KTNLD
971
LGPTA
976
PSLEK
981
EKTLC
986
LSTPS
991
SSTVK
996
HSTSS
1001
IGSML
1006
AQADK
1011
LPMTD
1016
KRVAS
1021
LLKKA
1026
KAQLC
1031
KIEKS
1036
KSLKQ
1041
TDQPK
1046
AQGQE
1051
SDSSE
1056
TSVRG
1061
PRIKH
1066
VCRRA
1071
AVALG
1076
RKRAV
1081
FPDDM
1086
PTLSA
1091
LPWEE
1096
REKIL
1101
SSMGN
1106
DDKSS
1111
IAGSE
1116
DAEPL
1121
APPIK
1126
PIKPV
1131
TRNKA
1136
PQEPP
1141
VKKGR
1146
RSRRC
1151
GQCPG
1156
CQVPE
1161
DCGVC
1166
TNCLD
1171
KPKFG
1176
GRNIK
1181
KQCCK
1186
MRKCQ
1191
NLQWM
1196
PSKAY
1201
LQKQA
1206
KAVKK
1211
KEKKS
1216
KTSEK
1221
KDSKE
1226
SSVVK
1231
NVVDS
1236
SQKPT
1241
PSARE
1246
DPAPK
1251
KSSSE
1256
PPPRK
1261
PVEEK
1266
SEEGN
1271
VSAPG
1276
PESKQ
1281
ATTPA
1286
SRKSS
1291
KQVSQ
1296
PALVI
1301
PPQPP
1306
TTGPP
1311
RKEVP
1316
KTTPS
1321
EPKKK
1326
QPPPP
1331
ESGPE
1336
QSKQK
1341
KVAPR
1346
PSIPV
1351
KQKPK
1356
EKEKP
1361
PPVNK
1366
QENAG
1371
TLNIL
1376
STLSN
1381
GNSSK
1386
QKIPA
1391
DGVHR
1396
IRVDF
1401
KEDCE
1406
AENVW
1411
EMGGL
1416
GILTS
1421
VPITP
1426
RVVCF
1431
LCASS
1436
GHVEF
1441
VYCQV
1446
CCEPF
1451
HKFCL
1456
EENER
1461
PLEDQ
1466
LENWC
1471
CRRCK
1476
FCHVC
1481
GRQHQ
1486
ATKQL
1491
LECNK
1496
CRNSY
1501
HPECL
1506
GPNYP
1511
TKPTK
1516
KKKVW
1521
ICTKC
1526
VRCKS
1531
CGSTT
1536
PGKGW
1541
DAQWS
1546
HDFSL
1551
CHDCA
1556
KLFAK
1561
GNFCP
1566
LCDKC
1571
YDDDD
1576
YESKM
1581
MQCGK
1586
CDRWV
1591
HSKCE
1596
NLSGT
1601
EDEMY
1606
EILSN
1611
LPESV
1616
AYTCV
1621
NCTER
1626
HPAEW
1631
RLALE
1636
KELQI
1641
SLKQV
1646
LTALL
1651
NSRTT
1656
SHLLR
1661
YRQAA
1666
KPPDL
1671
NPETE
1676
ESIPS
1681
RSSPE
1686
GPDPP
1691
VLTEV
1696
SKQDD
1701
QQPLD
1706
LEGVK
1711
RKMDQ
1716
GNYTS
1721
VLEFS
1726
DDIVK
1731
IIQAA
1736
INSDG
1741
GQPEI
1746
KKANS
1751
MVKSF
1756
FIRQM
1761
ERVFP
1766
WFSVK
1771
KSRFW
1776
EPNKV
1781
SSNSG
1786
MLPNA
1791
VLPPS
1796
LDHNY
1801
AQWQE
1806
REENS
1811
HTEQP
1816
PLMKK
1821
IIPAP
1826
KPKGP
1831
GEPDS
1836
PTPLH
1841
PPTPP
1846
ILSTD
1851
RSRED
1856
SPELN
1861
PPPGI
1866
EDNRQ
1871
CALCL
1876
TYGDD
1881
SANDA
1886
GRLLY
1891
IGQNE
1896
WTHVN
1901
CALWS
1906
AEVFE
1911
DDDGS
1916
LKNVH
1921
MAVIR
1926
GKQLR
1931
CEFCQ
1936
KPGAT
1941
VGCCL
1946
TSCTS
1951
NYHFM
1956
CSRAK
1961
NCVFL
1966
DDKKV
1971
YCQRH
1976
RDLIK
1981
GEVVP
1986
ENGFE
1991
VFRRV
1996
FVDFE
2001
GISLR
2006
RKFLN
2011
GLEPE
2016
NIHMM
2021
IGSMT
2026
IDCLG
2031
ILNDL
2036
SDCED
2041
KLFPI
2046
GYQCS
2051
RVYWS
2056
TTDAR
2061
KRCVY
2066
TCKIV
2071
ECRPP
2076
VVEPD
2081
INSTV
2086
EHDEN
2091
RTIAH
2096
SPTSF
2101
TESSS
2106
KESQN
2111
TAEII
2116
SPPSP
2121
DRPPH
2126
SQTSG
2131
SCYYH
2136
VISKV
2141
PRIRT
2146
PSYSP
2151
TQRSP
2156
GCRPL
2161
PSAGS
2166
PTPTT
2171
HEIVT
2176
VGDPL
2181
LSSGL
2186
RSIGS
2191
RRHST
2196
SSLSP
2201
QRSKL
2206
RIMSP
2211
MRTGN
2216
TYSRN
2221
NVSSV
2226
STTGT
2231
ATDLE
2236
SSAKV
2241
VDHVL
2246
GPLNS
2251
STSLG
2256
QNTST
2261
SSNLQ
2266
RTVVT
2271
VGNKN
2276
SHLDG
2281
SSSSE
2286
MKQSS
2291
ASDLV
2296
SKSSS
2301
LKGEK
2306
TKVLS
2311
SKSSE
2316
GSAHN
2321
VAYPG
2326
IPKLA
2331
PQVHN
2336
TTSRE
2341
LNVSK
2346
IGSFA
2351
EPSSV
2356
SFSSK
2361
EALSF
2366
PHLHL
2371
RGQRN
2376
DRDQH
2381
TDSTQ
2386
SANSS
2391
PDEDT
2396
EVKTL
2401
KLSGM
2406
SNRSS
2411
IINEH
2416
MGSSS
2421
RDRRQ
2426
KGKKS
2431
CKETF
2436
KEKHS
2441
SKSFL
2446
EPGQV
2451
TTGEE
2456
GNLKP
2461
EFMDE
2466
VLTPE
2471
YMGQR
2476
PCNNV
2481
SSDKI
2486
GDKGL
2491
SMPGV
2496
PKAPP
2501
MQVEG
2506
SAKEL
2511
QAPRK
2516
RTVKV
2521
TLTPL
2526
KMENE
2531
SQSKN
2536
ALKES
2541
SPASP
2546
LQIES
2551
TSPTE
2556
PISAS
2561
ENPGD
2566
GPVAQ
2571
PSPNN
2576
TSCQD
2581
SQSNN
2586
YQNLP
2591
VQDRN
2596
LMLPD
2601
GPKPQ
2606
EDGSF
2611
KRRYP
2616
RRSAR
2621
ARSNM
2626
FFGLT
2631
PLYGV
2636
RSYGE
2641
EDIPF
2646
YSSST
2651
GKKRG
2656
KRSAE
2661
GQVDG
2666
ADDLS
2671
TSDED
2676
DLYYY
2681
NFTRT
2686
VISSG
2691
GEERL
2696
ASHNL
2701
FREEE
2706
QCDLP
2711
KISQL
2716
DGVDD
2721
GTESD
2726
TSVTA
2731
TTRKS
2736
SQIPK
2741
RNGKE
2746
NGTEN
2751
LKIDR
2756
PEDAG
2761
EKEHV
2766
TKSSV
2771
GHKNE
2776
PKMDN
2781
CHSVS
2786
RVKTQ
2791
GQDSL
2796
EAQLS
2801
SLESS
2806
RRVHT
2811
STPSD
2816
KNLLD
2821
TYNTE
2826
LLKSD
2831
SDNNN
2836
SDDCG
2841
NILPS
2846
DIMDF
2851
VLKNT
2856
PSMQA
2861
LGESP
2866
ESSSS
2871
ELLNL
2876
GEGLG
2881
LDSNR
2886
EKDMG
2891
LFEVF
2896
SQQLP
2901
TTEPV
2906
DSSVS
2911
SSISA
2916
EEQFE
2921
LPLEL
2926
PSDLS
2931
VLTTR
2936
SPTVP
2941
SQNPS
2946
RLAVI
2951
SDSGE
2956
KRVTI
2961
TEKSV
2966
ASSES
2971
DPALL
2976
SPGVD
2981
PTPEG
2986
HMTPD
2991
HFIQG
2996
HMDAD
3001
HISSP
3006
PCGSV
3011
EQGHG
3016
NNQDL
3021
TRNSS
3026
TPGLQ
3031
VPVSP
3036
TVPIQ
3041
NQKYV
3046
PNSTD
3051
SPGPS
3056
QISNA
3061
AVQTT
3066
PPHLK
3071
PATEK
3076
LIVVN
3081
QNMQP
3086
LYVLQ
3091
TLPNG
3096
VTQKI
3101
QLTSS
3106
VSSTP
3111
SVMET
3116
NTSVL
3121
GPMGG
3126
GLTLT
3131
TGLNP
3136
SLPTS
3141
QSLFP
3146
SASKG
3151
LLPMS
3156
HHQHL
3161
HSFPA
3166
ATQSS
3171
FPPNI
3176
SNPPS
3181
GLLIG
3186
VQPPP
3191
DPQLL
3196
VSESS
3201
QRTDL
3206
STTVA
3211
TPSSG
3216
LKKRP
3221
ISRLQ
3226
TRKNK
3231
KLAPS
3236
STPSN
3241
IAPSD
3246
VVSNM
3251
TLINF
3256
TPSQL
3261
PNHPS
3266
LLDLG
3271
SLNTS
3276
SHRTV
3281
PNIIK
3286
RSKSS
3291
IMYFE
3296
PAPLL
3301
PQSVG
3306
GTAAT
3311
AAGTS
3316
TISQD
3321
TSHLT
3326
SGSVS
3331
GLASS
3336
SSVLN
3341
VVSMQ
3346
TTTTP
3351
TSSAS
3356
VPGHV
3361
TLTNP
3366
RLLGT
3371
PDIGS
3376
ISNLL
3381
IKASQ
3386
QSLGI
3391
QDQPV
3396
ALPPS
3401
SGMFP
3406
QLGTS
3411
QTPST
3416
AAITA
3421
ASSIC
3426
VLPST
3431
QTTGI
3436
TAASP
3441
SGEAD
3446
EHYQL
3451
QHVNQ
3456
LLASK
3461
TGIHS
3466
SQRDL
3471
DSASG
3476
PQVSN
3481
FTQTV
3486
DAPNS
3491
MGLEQ
3496
NKALS
3501
SAVQA
3506
SPTSP
3511
GGSPS
3516
SPSSG
3521
QRSAS
3526
PSVPG
3531
PTKPK
3536
PKTKR
3541
FQLPL
3546
DKGNG
3551
KKHKV
3556
SHLRT
3561
SSSEA
3566
HIPDQ
3571
ETTSL
3576
TSGTG
3581
TPGAE
3586
AEQQD
3591
TASVE
3596
QSSQK
3601
ECGQP
3606
AGQVA
3611
VLPEV
3616
QVTQN
3621
PANEQ
3626
ESAEP
3631
KTVEE
3636
EESNF
3641
SSPLM
3646
LWLQQ
3651
EQKRK
3656
ESITE
3661
KKPKK
3666
GLVFE
3671
ISSDD
3676
GFQIC
3681
AESIE
3686
DAWKS
3691
LTDKV
3696
QEARS
3701
NARLK
3706
QLSFA
3711
GVNGL
3716
RMLGI
3721
LHDAV
3726
VFLIE
3731
QLSGA
3736
KHCRN
3741
YKFRF
3746
HKPEE
3751
ANEPP
3756
LNPHG
3761
SARAE
3766
VHLRK
3771
SAFDM
3776
FNFLA
3781
SKHRQ
3786
PPEYN
3791
PNDEE
3796
EEEVQ
3801
LKSAR
3806
RATSM
3811
DLPMP
3816
MRFRH
3821
LKKTS
3826
KEAVG
3831
VYRSP
3836
IHGRG
3841
LFCKR
3846
NIDAG
3851
EMVIE
3856
YAGNV
3861
IRSIQ
3866
TDKRE
3871
KYYDS
3876
KGIGC
3881
YMFRI
3886
DDSEV
3891
VDATM
3896
HGNAA
3901
RFINH
3906
SCEPN
3911
CYSRV
3916
INIDG
3921
QKHIV
3926
IFAMR
3931
KIYRG
3936
EELTY
3941
DYKFP
3946
IEDAS
3951
NKLPC
3956
NCGAK
3961
KCRKF
3966
LN
3971
Mutation Information
DNA mutation:
None
Peptide Range:
3230 ~ 3253
Mut AA position:
3239 (10 in Wild Type peptide)
Alignment
Wild Type:
"---QTRKNKKLAP-----------
|||||||||.
Mutant:
SRLQTRKNKKLALSSTPSNIAPSD"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) MLL
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
None
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay