Immunogenicity 485
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
ABCB5
Transcript ID
None
HLA INFO
B*18:01
TCR INFO
No TCR info found!
Full length protein sequence (1257 aa)
MENSE
1
RAEEM
6
QENYQ
11
RNGTA
16
EEQPK
21
LRKEA
26
VGSIE
31
IFRFA
36
DGLDI
41
TLMIL
46
GILAS
51
LVNGA
56
CLPLM
61
PLVLG
66
EMSDN
71
LISGC
76
LVQTN
81
TTNYQ
86
NCTQS
91
QEKLN
96
EDMTL
101
LTLYY
106
VGIGV
111
AALIF
116
GYIQI
121
SLWII
126
TAARQ
131
TKRIR
136
KQFFH
141
SVLAQ
146
DIGWF
151
DSCDI
156
GELNT
161
RMTDD
166
IDKIS
171
DGIGD
176
KIALL
181
FQNMS
186
TFSIG
191
LAVGL
196
VKGWK
201
LTLVT
206
LSTSP
211
LIMAS
216
AAACS
221
RMVIS
226
LTSKE
231
LSAYS
236
KAGAV
241
AEEVL
246
SSIRT
251
VIAFR
256
AQEKE
261
LQRYT
266
QNLKD
271
AKDFG
276
IKRTI
281
ASKVS
286
LGAVY
291
FFMNG
296
TYGLA
301
FWYGT
306
SLILN
311
GEPGY
316
TIGTV
321
LAVFF
326
SVIHS
331
SYCIG
336
AAVPH
341
FETFA
346
IARGA
351
AFHIF
356
QVIDK
361
KPSID
366
NFSTA
371
GYKPE
376
SIEGT
381
VEFKN
386
VSFNY
391
PSRPS
396
IKILK
401
GLNLR
406
IKSGE
411
TVALV
416
GLNGS
421
GKSTV
426
VQLLQ
431
RLYDP
436
DDGFI
441
MVDEN
446
DIRAL
451
NVRHY
456
RDHIG
461
VVSQE
466
PVLFG
471
TTISN
476
NIKYG
481
RDDVT
486
DEEME
491
RAARE
496
ANAYD
501
FIMEF
506
PNKFN
511
TLVGE
516
KGAQM
521
SGGQK
526
QRIAI
531
ARALV
536
RNPKI
541
LILDE
546
ATSAL
551
DSESK
556
SAVQA
561
ALEKA
566
SKGRT
571
TIVVA
576
HRLST
581
IRSAD
586
LIVTL
591
KDGML
596
AEKGA
601
HAELM
606
AKRGL
611
YYSLV
616
MSQDI
621
KKADE
626
QMESM
631
TYSTE
636
RKTNS
641
LPLHS
646
VKSIK
651
SDFID
656
KAEES
661
TQSKE
666
ISLPE
671
VSLLK
676
ILKLN
681
KPEWP
686
FVVLG
691
TLASV
696
LNGTV
701
HPVFS
706
IIFAK
711
IITMF
716
GNNDK
721
TTLKH
726
DAEIY
731
SMIFV
736
ILGVI
741
CFVSY
746
FMQGL
751
FYGRA
756
GEILT
761
MRLRH
766
LAFKA
771
MLYQD
776
IAWFD
781
EKENS
786
TGGLT
791
TILAI
796
DIAQI
801
QGATG
806
SRIGV
811
LTQNA
816
TNMGL
821
SVIIS
826
FIYGW
831
EMTFL
836
ILSIA
841
PVLAV
846
TGMIE
851
TAAMT
856
GFANK
861
DKQEL
866
KHAGK
871
IATEA
876
LENIR
881
TIVSL
886
TREKA
891
FEQMY
896
EEMLQ
901
TQHRN
906
TSKKA
911
QIIGS
916
CYAFS
921
HAFIY
926
FAYAA
931
GFRFG
936
AYLIQ
941
AGRMT
946
PEGMF
951
IVFTA
956
IAYGA
961
MAIGE
966
TLVLA
971
PEYSK
976
AKSGA
981
AHLFA
986
LLEKK
991
PNIDS
996
RSQEG
1001
KKPDT
1006
CEGNL
1011
EFREV
1016
SFFYP
1021
CRPDV
1026
FILRG
1031
LSLSI
1036
ERGKT
1041
VAFVG
1046
SSGCG
1051
KSTSV
1056
QLLQR
1061
LYDPV
1066
QGQVL
1071
FDGVD
1076
AKELN
1081
VQWLR
1086
SQIAI
1091
VPQEP
1096
VLFNC
1101
SIAEN
1106
IAYGD
1111
NSRVV
1116
PLDEI
1121
KEAAN
1126
AANIH
1131
SFIEG
1136
LPEKY
1141
NTQVG
1146
LKGAQ
1151
LSGGQ
1156
KQRLA
1161
IARAL
1166
LQKPK
1171
ILLLD
1176
EATSA
1181
LDNDS
1186
EKVVQ
1191
HALDK
1196
ARTGR
1201
TCLVV
1206
THRLS
1211
AIQNA
1216
DLIVV
1221
LHNGK
1226
IKEQG
1231
THQEL
1236
LRNRD
1241
IYFKL
1246
VNAQS
1251
VQ
1256
Mutation Information
DNA mutation:
None
Peptide Range:
629 ~ 651
Mut AA position:
632 (4 in Wild Type peptide)
Alignment
Wild Type:
"--------DEQMESMTY------
|||.|||||
Mutant:
MSQDIKKADEQIESMTYSTERKT"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) ABCB5
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
None
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay