Immunogenicity 4850
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
DYSF
Transcript ID
NM_001130455
HLA INFO
B*18:01
TCR INFO
No TCR info found!
Full length protein sequence (2081 aa)
MLCCL
1
LVRAS
6
NLPSA
11
KKDRR
16
SDPVA
21
SLTFR
26
GVKKR
31
TKVIK
36
NSVNP
41
VWNEG
46
FEWDL
51
KGIPL
56
DQGSE
61
LHVVV
66
KDHET
71
MGRNR
76
FLGEA
81
KVPLR
86
EVLAT
91
PSLSA
96
SFNAP
101
LLDTK
106
KQPTG
111
ASLVL
116
QVSYT
121
PLPGA
126
VPLFP
131
PPTPL
136
EPSPT
141
LPDLD
146
VVADT
151
GGEED
156
TEDQG
161
LTGDE
166
AEPFL
171
DQSGG
176
PGAPT
181
TPRKL
186
PSRPP
191
PHYPG
196
IKRKR
201
SAPTS
206
RKLLS
211
DKPQD
216
FQIRV
221
QVIEG
226
RQLPG
231
VNIKP
236
VVKVT
241
AAGQT
246
KRTRI
251
HKGNS
256
PLFNE
261
TLFFN
266
LFDSP
271
GELFD
276
EPIFI
281
TVVDS
286
RSLRT
291
DALLG
296
EFRMD
301
VGTIY
306
REPRH
311
AYLRK
316
WLLLS
321
DPDDF
326
SAGAR
331
GYLKT
336
SLCVL
341
GPGDE
346
APLER
351
KDPSE
356
DKEDI
361
ESNLL
366
RPTGV
371
ALRGA
376
HFCLK
381
VFRAE
386
DLPQM
391
DDAVM
396
DNVKQ
401
IFGFE
406
SNKKN
411
LVDPF
416
VEVSF
421
AGKML
426
CSKIL
431
EKTAN
436
PQWNQ
441
NITLP
446
AMFPS
451
MCEKM
456
RIRII
461
DWDRL
466
THNDI
471
VATTY
476
LSMSK
481
ISAPG
486
GEIEE
491
EPAGA
496
VKPSK
501
ASDLD
506
DYLGF
511
LPTFG
516
PCYIN
521
LYGSP
526
REFTG
531
FPDPY
536
TELNT
541
GKGEG
546
VAYRG
551
RLLLS
556
LETKL
561
VEHSE
566
QKVED
571
LPADD
576
ILRVE
581
KYLRR
586
RKYSL
591
FAAFY
596
SATML
601
QDVDD
606
AIQFE
611
VSIGN
616
YGNKF
621
DMTCL
626
PLAST
631
TQYSR
636
AVFDG
641
CHYYY
646
LPWGN
651
VKPVV
656
VLSSY
661
WEDIS
666
HRIET
671
QNQLL
676
GIADR
681
LEAGL
686
EQVHL
691
ALKAQ
696
CSTED
701
VDSLV
706
AQLTD
711
ELIAG
716
CSQPL
721
GDIHE
726
TPSAT
731
HLDQY
736
LYQLR
741
THHLS
746
QITEA
751
ALALK
756
LGHSE
761
LPAAL
766
EQAED
771
WLLRL
776
RALAE
781
EPQNS
786
LPDIV
791
IWMLQ
796
GDKRV
801
AYQRV
806
PAHQV
811
LFSRR
816
GANYC
821
GKNCG
826
KLQTI
831
FLKYP
836
MEKVP
841
GARMP
846
VQIRV
851
KLWFG
856
LSVDE
861
KEFNQ
866
FAEGK
871
LSVFA
876
ETYEN
881
ETKLA
886
LVGNW
891
GTTGL
896
TYPKF
901
SDVTG
906
KIKLP
911
KDSFR
916
PSAGW
921
TWAGD
926
WFVCP
931
EKTLL
936
HDMDA
941
GHLSF
946
VEEVF
951
ENQTR
956
LPGGQ
961
WIYMS
966
DNYTD
971
VNGEK
976
VLPKD
981
DIECP
986
LGWKW
991
EDEEW
996
STDLN
1001
RAVDE
1006
QGWEY
1011
SITIP
1016
PERKP
1021
KHWVP
1026
AEKMY
1031
YTHRR
1036
RRWVR
1041
LRRRD
1046
LSQME
1051
ALKRH
1056
RQAEA
1061
EGEGW
1066
EYASL
1071
FGWKF
1076
HLEYR
1081
KTDAF
1086
RRRRW
1091
RRRME
1096
PLEKT
1101
GPAAV
1106
FALEG
1111
ALGGV
1116
MDDKS
1121
EDSMS
1126
VSTLS
1131
FGVNR
1136
PTISC
1141
IFDYG
1146
NRYHL
1151
RCYMY
1156
QARDL
1161
AAMDK
1166
DSFSD
1171
PYAIV
1176
SFLHQ
1181
SQKTV
1186
VVKNT
1191
LNPTW
1196
DQTLI
1201
FYEIE
1206
IFGEP
1211
ATVAE
1216
QPPSI
1221
VVELY
1226
DHDTY
1231
GADEF
1236
MGRCI
1241
CQPSL
1246
ERMPR
1251
LAWFP
1256
LTRGS
1261
QPSGE
1266
LLASF
1271
ELIQR
1276
EKPAI
1281
HHIPG
1286
FEVQE
1291
TSRIL
1296
DESED
1301
TDLPY
1306
PPPQR
1311
EANIY
1316
MVPQN
1321
IKPAL
1326
QRTAI
1331
EILAW
1336
GLRNM
1341
KSYQL
1346
ANISS
1351
PSLVV
1356
ECGGQ
1361
TVQSC
1366
VIRNL
1371
RKNPN
1376
FDICT
1381
LFMEV
1386
MLPRE
1391
ELYCP
1396
PITVK
1401
VIDNR
1406
QFGRR
1411
PVVGQ
1416
CTIRS
1421
LESFL
1426
CDPYS
1431
AESPS
1436
PQGGP
1441
DDVSL
1446
LSPGE
1451
DVLID
1456
IDDKE
1461
PLIPI
1466
QEEEF
1471
IDWWS
1476
KFFAS
1481
IGERE
1486
KCGSY
1491
LEKDF
1496
DTLKV
1501
YDTQL
1506
ENVEA
1511
FEGLS
1516
DFCNT
1521
FKLYR
1526
GKTQE
1531
ETEDP
1536
SVIGE
1541
FKGLF
1546
KIYPL
1551
PEDPA
1556
IPMPP
1561
RQFHQ
1566
LAAQG
1571
PQECL
1576
VRIYI
1581
VRAFG
1586
LQPKD
1591
PNGKC
1596
DPYIK
1601
ISIGK
1606
KSVSD
1611
QDNYI
1616
PCTLE
1621
PVFGK
1626
MFELT
1631
CTLPL
1636
EKDLK
1641
ITLYD
1646
YDLLS
1651
KDEKI
1656
GETVV
1661
DLENR
1666
LLSKF
1671
GARCG
1676
LPQTY
1681
CVSGP
1686
NQWRD
1691
QLRPS
1696
QLLHL
1701
FCQQH
1706
RVKAP
1711
VYRTD
1716
RVMFQ
1721
DKEYS
1726
IEEIE
1731
AGRIP
1736
NPHLG
1741
PVEER
1746
LALHV
1751
LQQQG
1756
LVPEH
1761
VESRP
1766
LYSPL
1771
QPDIE
1776
QGKLQ
1781
MWVDL
1786
FPKAL
1791
GRPGP
1796
PFNIT
1801
PRRAR
1806
RFFLR
1811
CIIWN
1816
TRDVI
1821
LDDLS
1826
LTGEK
1831
MSDIY
1836
VKGWM
1841
IGFEE
1846
HKQKT
1851
DVHYR
1856
SLGGE
1861
GNFNW
1866
RFIFP
1871
FDYLP
1876
AEQVC
1881
TIAKK
1886
DAFWR
1891
LDKTE
1896
SKIPA
1901
RVVFQ
1906
IWDND
1911
KFSFD
1916
DFLGS
1921
LQLDL
1926
NRMPK
1931
PAKTA
1936
KKCSL
1941
DQLDD
1946
AFHPE
1951
WFVSL
1956
FEQKT
1961
VKGWW
1966
PCVAE
1971
EGEKK
1976
ILAGK
1981
LEMTL
1986
EIVAE
1991
SEHEE
1996
RPAGQ
2001
GRDEP
2006
NMNPK
2011
LEDPR
2016
RPDTS
2021
FLWFT
2026
SPYKT
2031
MKFIL
2036
WRRFR
2041
WAIIL
2046
FIILF
2051
ILLLF
2056
LAIFI
2061
YAFPN
2066
YAAMK
2071
LVKPF
2076
S
2081
Mutation Information
DNA mutation:
None
Peptide Range:
1688 ~ 1712
Mut AA position:
1700 (13 in Wild Type peptide)
Alignment
Wild Type:
"SGPNQWRDQLRPSQLLHLFCQQHRV
||||||||||||.||||||||||||
Mutant:
SGPNQWRDQLRPPQLLHLFCQQHRV"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) DYSF
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay