Immunogenicity 4853

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
UHRF2
Transcript ID
NM_152896
HLA INFO
A*03:01
TCR INFO

No TCR info found!

T cell Tumor cell A*03:01
sequence
Full length protein sequence (802 aa)
MWIQV
1
RTIDG
6
SKTCT
11
IEDVS
16
RKATI
21
EELRE
26
RVWAL
31
FDVRP
36
ECQRL
41
FYRGK
46
QLENG
51
YTLFD
56
YDVGL
61
NDIIQ
66
LLVRP
71
DPDHL
76
PGTST
81
QIEAK
86
PCSNS
91
PPKVK
96
KAPRV
101
GPSNQ
106
PSTSA
111
RARLI
116
DPGFG
121
IYKVN
126
ELVDA
131
RDVGL
136
GAWFE
141
AHIHS
146
VTRAS
151
DGQSR
156
GKTPL
161
KNGSS
166
CKRTN
171
GNIKH
176
KSKEN
181
TNKLD
186
SVPST
191
SNSDC
196
VAADE
201
DVIYH
206
IQYDE
211
YPESG
216
TLEMN
221
VKDLR
226
PRART
231
ILKWN
236
ELNVG
241
DVVMV
246
NYNVE
251
SPGQR
256
GFWFD
261
AEITT
266
LKTIS
271
RTKKE
276
LRVKI
281
FLGGS
286
EGTLN
291
DCKII
296
SVDEI
301
FKIER
306
PGAHP
311
LSFAD
316
GKFLR
321
RNDPE
326
CDLCG
331
GDPEK
336
KCHSC
341
SCRVC
346
GGKHE
351
PNMQL
356
LCDEC
361
NVAYH
366
IYCLN
371
PPLDK
376
VPEEE
381
YWYCP
386
SCKTD
391
SSEVV
396
KAGER
401
LKMSK
406
KKAKM
411
PSAST
416
ESRRD
421
WGRGM
426
ACVGR
431
TRECT
436
IVPSN
441
HYGPI
446
PGIPV
451
GSTWR
456
FRVQV
461
SEAGV
466
HRPHV
471
GGIHG
476
RSNDG
481
AYSLV
486
LAGGF
491
ADEVD
496
RGDEF
501
TYTGS
506
GGKNL
511
AGNKR
516
IGAPS
521
ADQTL
526
TNMNR
531
ALALN
536
CDAPL
541
DDKIG
546
AESRN
551
WRAGK
556
PVRVI
561
RSFKG
566
RKISK
571
YAPEE
576
GNRYD
581
GIYKV
586
VKYWP
591
EISSS
596
HGFLV
601
WRYLL
606
RRDDV
611
EPAPW
616
TSEGI
621
ERSRR
626
LCLRL
631
QYPAG
636
YPSDK
641
EGKKP
646
KGQSK
651
KQPSG
656
TTKRP
661
ISDDD
666
CPSAS
671
KVYKA
676
SDSAE
681
AIEAF
686
QLTPQ
691
QQHLI
696
REDCQ
701
NQKLW
706
DEVLS
711
HLVEG
716
PNFLK
721
KLEQS
726
FMCVC
731
CQELV
736
YQPVT
741
TECFH
746
NVCKD
751
CLQRS
756
FKAQV
761
FSCPA
766
CRHDL
771
GQNYI
776
MIPNE
781
ILQTL
786
LDLFF
791
PGYSK
796
GR
801
Mutation Information
DNA mutation:
None
Peptide Range:
424 ~ 448
Mut AA position:
436 (13 in Wild Type peptide)
Alignment
Wild Type:
"RDWGRGMACVGRTRECTIVPSNHYG
||||||||||||.||||||||||||
Mutant:
RDWGRGMACVGRRRECTIVPSNHYG"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) UHRF2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay