Immunogenicity 4865
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
PCDH8
Transcript ID
NM_002590
HLA INFO
B*18:01
TCR INFO
No TCR info found!
Full length protein sequence (1070 aa)
MSPVR
1
RWGSP
6
CLFPL
11
QLFSL
16
CWVLS
21
VAQSK
26
TVRYS
31
TFEED
36
APGTV
41
IGTLA
46
EDLHM
51
KVSGD
56
TSFRL
61
MKQFN
66
SSLLR
71
VREGD
76
GQLTV
81
GDAGL
86
DRERL
91
CGQAP
96
QCVLA
101
FDVVS
106
FSQEQ
111
FRLVH
116
VEVEV
121
RDVND
126
HAPRF
131
PRAQI
136
PVEVS
141
EGAAV
146
GTRIP
151
LEVPV
156
DEDVG
161
ANGLQ
166
TVRLA
171
EPHSP
176
FRVEL
181
QTRAD
186
GAQCA
191
DLVLL
196
QELDR
201
ESQAA
206
YSLEL
211
VAQDG
216
GRPPR
221
SATAA
226
LSVRV
231
LDAND
236
HSPAF
241
PQGAV
246
AEVEL
251
AEDAP
256
VGSLL
261
LDLDA
266
ADPDE
271
GPNGD
276
VVFAF
281
GARTP
286
PEARR
291
LFRLD
296
PRSGR
301
LTLAG
306
PVDYE
311
RQDTY
316
ELDVR
321
AQDRG
326
PGPRA
331
ATCKV
336
IVRIR
341
DVNDN
346
APDIA
351
ITPLA
356
APGAP
361
ATSPF
366
AAAAA
371
AAALG
376
GADAS
381
SPAGA
386
GTPEA
391
GATSL
396
VPEGA
401
ARESL
406
VALVS
411
TSDRD
416
SGANG
421
QVRCA
426
LYGHE
431
HFRLQ
436
PAYAG
441
SYLVV
446
TAASL
451
DRERI
456
AEYNL
461
TLVAE
466
DRGAP
471
PLRTV
476
RPYTV
481
RVGDE
486
NDNAP
491
LFTRP
496
VYEVS
501
VRENN
506
PPGAY
511
LATVA
516
ARDRD
521
LGRNG
526
QVTYR
531
LLEAE
536
VGRAG
541
GAVST
546
YVSVD
551
PATGA
556
IYALR
561
SFDYE
566
TLRQL
571
DVRIQ
576
ASDGG
581
SPQLS
586
SSALV
591
QVRVL
596
DQNDH
601
APVLV
606
HPAPA
611
NGSLE
616
VAVPG
621
RTAKD
626
TVVAR
631
VQARD
636
ADEGA
641
NGELA
646
FELQQ
651
QEPRE
656
AFAIG
661
RRTGE
666
ILLTG
671
DLSQE
676
PPGRV
681
FRALL
686
VISDG
691
GRPPL
696
TTTAT
701
VSFVV
706
TAGGG
711
RGPAA
716
PASAG
721
SPERS
726
RPPGS
731
RLGVS
736
GSVLQ
741
WDTPL
746
IVIIV
751
LAGSC
756
TLLLA
761
AIIAI
766
ATTCN
771
RRKKE
776
VRKGG
781
ALREE
786
RPGAA
791
GGGAS
796
APGSP
801
EEAAR
806
GAGPR
811
PNMFD
816
VLTFP
821
GTGKA
826
PFGSP
831
AADAP
836
PPAVA
841
AAEVP
846
GSEGG
851
SATGE
856
SACHF
861
EGQQR
866
LRGAH
871
AEPYG
876
ASPGF
881
GKEPA
886
PPVAV
891
WKGHS
896
FNTIS
901
GREAE
906
KFSGK
911
DSGKG
916
DSDFN
921
DSDSD
926
ISGDA
931
LKKDL
936
INHMQ
941
SGLWA
946
CTAEC
951
KILGH
956
SDRCW
961
SPSCS
966
GPNAH
971
PSPHP
976
PAQMS
981
TFCKS
986
TSLPR
991
DPLRR
996
DNYYQ
1001
AQLPK
1006
TVGLQ
1011
SVYEK
1016
VLHRD
1021
YDRTV
1026
TLLSP
1031
PRPGR
1036
LPDLQ
1041
EIGVP
1046
LYQSP
1051
PGRYL
1056
SPKKG
1061
ANENV
1066
Mutation Information
DNA mutation:
None
Peptide Range:
411 ~ 435
Mut AA position:
423 (13 in Wild Type peptide)
Alignment
Wild Type:
"VALVSTSDRDSGANGQVRCALYGHE
||||||||||||.||||||||||||
Mutant:
VALVSTSDRDSGTNGQVRCALYGHE"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) PCDH8
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay