Immunogenicity 4879
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
SPTB
Transcript ID
NM_001024858
HLA INFO
DQA*05:01 / DQB*02:02
TCR INFO
No TCR info found!
Full length protein sequence (2328 aa)
MTSAT
1
EFENV
6
GNQPP
11
YSRIN
16
ARWDA
21
PDDEL
26
DNDNS
31
SARLF
36
ERSRI
41
KALAD
46
EREVV
51
QKKTF
56
TKWVN
61
SHLAR
66
VSCRI
71
TDLYK
76
DLRDG
81
RMLIK
86
LLEVL
91
SGEML
96
PKPTK
101
GKMRI
106
HCLEN
111
VDKAL
116
QFLKE
121
QRVHL
126
ENMGS
131
HDIVD
136
GNHRL
141
VLGLI
146
WTIIL
151
RFQIQ
156
DIVVQ
161
TQEGR
166
ETRSA
171
KDALL
176
LWCQM
181
KTAGY
186
PHVNV
191
TNFTS
196
SWKDG
201
LAFNA
206
LIHKH
211
RPDLI
216
DFDKL
221
KDSNA
226
RHNLE
231
HAFNV
236
AERQL
241
GIIPL
246
LDPED
251
VFTEN
256
PDEKS
261
IITYV
266
VAFYH
271
YFSKM
276
KVLAV
281
EGKRV
286
GKVID
291
HAIET
296
EKMIE
301
KYSGL
306
ASDLL
311
TWIEQ
316
TITVL
321
NSRKF
326
ANSLT
331
GVQQQ
336
LQAFS
341
TYRTV
346
EKPPK
351
FQEKG
356
NLEVL
361
LFTIQ
366
SRMRA
371
NNQKV
376
YTPHD
381
GKLVS
386
DINRA
391
WESLE
396
EAEYR
401
RELAL
406
RNELI
411
RQEKL
416
EQLAR
421
RFDRK
426
AAMRE
431
TWLSE
436
NQRLV
441
AQDNF
446
GYDLA
451
AVEAA
456
KKKHE
461
AIETD
466
TAAYE
471
ERVRA
476
LEDLA
481
QELEK
486
ENYHD
491
QKRIT
496
ARKDN
501
ILRLW
506
SYLQE
511
LLQSR
516
RQRLE
521
TTLAL
526
QKLFQ
531
DMLHS
536
IDWMD
541
EIKAH
546
LLSAE
551
FGKHL
556
LEVED
561
LLQKH
566
KLMEA
571
DIAIQ
576
GDKVK
581
AITAA
586
TLKFT
591
EGKGY
596
QPCDP
601
QVIQD
606
RISHL
611
EQCFE
616
ELSNM
621
AAGRK
626
AQLEQ
631
SKRLW
636
KFFWE
641
MDEAE
646
SWIKE
651
KEQIY
656
SSLDY
661
GKDLT
666
SVLIL
671
QRKHK
676
AFEDE
681
LRGLD
686
AHLEQ
691
IFQEA
696
HGMVA
701
RKQFG
706
HPQIE
711
ARIKE
716
VSAQW
721
DQLKD
726
LAAFC
731
KKNLQ
736
DAENF
741
FQFQG
746
DADDL
751
KAWLQ
756
DAHRL
761
LSGED
766
VGQDE
771
GATRA
776
LGKKH
781
KDFLE
786
ELEES
791
RGVME
796
HLEQQ
801
AQGFP
806
EEFRD
811
SPDVT
816
HRLQA
821
LRELY
826
QQVVA
831
QADLR
836
QQRLQ
841
EALDL
846
YTVFG
851
ETDAC
856
ELWMG
861
EKEKW
866
LAEME
871
MPDTL
876
EDLEV
881
VQHRF
886
DILDQ
891
EMKTL
896
MTQID
901
GVNLA
906
ANSLV
911
ESGHP
916
RSREV
921
KQYQD
926
HLNTR
931
WQAFQ
936
TLVSE
941
RREAV
946
DSALR
951
VHNYC
956
VDCEE
961
TSKWI
966
TDKTK
971
VVEST
976
KDLGR
981
DLAGI
986
IAIQR
991
KLSGL
996
ERDVA
1001
AIQAR
1006
VDALE
1011
RESQQ
1016
LMDSH
1021
PEQKE
1026
DIGQR
1031
QKHLE
1036
ELWQG
1041
LQQSL
1046
QGQED
1051
LLGEV
1056
SQLQA
1061
FLQDL
1066
DDFQA
1071
WLSIT
1076
QKAVA
1081
SEDMP
1086
ESLPE
1091
AEQLL
1096
QQHAG
1101
IKDEI
1106
DGHQD
1111
SYQRV
1116
KESGE
1121
KVIQG
1126
QTDPE
1131
YLLLG
1136
QRLEG
1141
LDTGW
1146
NALGR
1151
MWESR
1156
SHTLA
1161
QCLGF
1166
QEFQK
1171
DAKQA
1176
EAILS
1181
NQEYT
1186
LAHLE
1191
PPDSL
1196
EAAEA
1201
GIRKF
1206
EDFLG
1211
SMENN
1216
RDKVL
1221
SPVDS
1226
GNKLV
1231
AEGNL
1236
YSDKI
1241
KEKVQ
1246
LIEDR
1251
HRKNN
1256
EKAQE
1261
ASVLL
1266
RDNLE
1271
LQNFL
1276
QNCQE
1281
LTLWI
1286
NDKLL
1291
TSQDV
1296
SYDEA
1301
RNLHN
1306
KWLKH
1311
QAFVA
1316
ELASH
1321
EGWLE
1326
NIDAE
1331
GKQLM
1336
DEKPQ
1341
FTALV
1346
SQKLE
1351
ALHRL
1356
WDELQ
1361
ATTKE
1366
KTQHL
1371
SAARS
1376
SDLRL
1381
QTHAD
1386
LNKWI
1391
SAMED
1396
QLRSD
1401
DPGKD
1406
LTSVN
1411
RMLAK
1416
LKRVE
1421
DQVNV
1426
RKEEL
1431
GELFA
1436
QVPSM
1441
GEEGG
1446
DADLS
1451
IEKRF
1456
LDLLE
1461
PLGRR
1466
KKQLE
1471
SSRAK
1476
LQISR
1481
DLEDE
1486
TLWVE
1491
ERLPL
1496
AQSAD
1501
YGTNL
1506
QTVQL
1511
FMKKN
1516
QTLQN
1521
EILGH
1526
TPRVE
1531
DVLQR
1536
GQQLV
1541
EAAEI
1546
DCQDL
1551
EERLG
1556
HLQSS
1561
WDRLR
1566
EAAAG
1571
RLQRL
1576
RDANE
1581
AQQYY
1586
LDADE
1591
AEAWI
1596
GEQEL
1601
YVISD
1606
EIPKD
1611
EEGAI
1616
VMLKR
1621
HLRQQ
1626
RAVED
1631
YGRNI
1636
KQLAS
1641
RAQGL
1646
LSAGH
1651
PEGEQ
1656
IIRLQ
1661
GQVDK
1666
HYAGL
1671
KDVAE
1676
ERKRK
1681
LENMY
1686
HLFQL
1691
KRETD
1696
DLEQW
1701
ISEKE
1706
LVASS
1711
PEMGQ
1716
DFDHV
1721
TLLRD
1726
KFRDF
1731
ARETG
1736
AIGQE
1741
RVDNV
1746
NAFIE
1751
RLIDA
1756
GHSEA
1761
ATIAE
1766
WKDGL
1771
NEMWA
1776
DLLEL
1781
IDTRM
1786
QLLAA
1791
SYDLH
1796
RYFYT
1801
GAEIL
1806
GLIDE
1811
KHREL
1816
PEDVG
1821
LDAST
1826
AESFH
1831
RVHTA
1836
FEREL
1841
HLLGV
1846
QVQQF
1851
QDVAT
1856
RLQTA
1861
YAGEK
1866
AEAIQ
1871
NKEQE
1876
VSAAW
1881
QALLD
1886
ACAGR
1891
RTQLV
1896
DTADK
1901
FRFFS
1906
MARDL
1911
LSWME
1916
SIIRQ
1921
IETQE
1926
RPRDV
1931
SSVEL
1936
LMKYH
1941
QGINA
1946
EIETR
1951
SKNFS
1956
ACLEL
1961
GESLL
1966
QRQHQ
1971
ASEEI
1976
REKLQ
1981
QVMSR
1986
RKEMN
1991
EKWEA
1996
RWERL
2001
RMLLE
2006
VCQFS
2011
RDASV
2016
AEAWL
2021
IAQEP
2026
YLASG
2031
DFGHT
2036
VDSVE
2041
KLIKR
2046
HEAFE
2051
KSTAS
2056
WAERF
2061
AALEK
2066
PTTLE
2071
LKERQ
2076
IAERP
2081
AEETG
2086
PQEEE
2091
GETAG
2096
EAPVS
2101
HHAAT
2106
ERTSP
2111
GEEEG
2116
TWPQN
2121
LQQPP
2126
PPGQH
2131
KDGQK
2136
STGDE
2141
RPTTE
2146
PLFKV
2151
LDTPL
2156
SEGDE
2161
PATLP
2166
APRDH
2171
GQSVQ
2176
MEGYL
2181
GRKHD
2186
LEGPN
2191
KKASN
2196
RSWNN
2201
LYCVL
2206
RNSEL
2211
TFYKD
2216
AKNLA
2221
LGMPY
2226
HGEEP
2231
LALRH
2236
AICEI
2241
AANYK
2246
KKKHV
2251
FKLRL
2256
SNGSE
2261
WLFHG
2266
KDEEE
2271
MLSWL
2276
QGVST
2281
AINES
2286
QSIRV
2291
KAQSL
2296
PLPSL
2301
SGPDA
2306
SLGKK
2311
DKEKR
2316
FSFFP
2321
KKK
2326
Mutation Information
DNA mutation:
None
Peptide Range:
1507 ~ 1531
Mut AA position:
1519 (13 in Wild Type peptide)
Alignment
Wild Type:
"GTNLQTVQLFMKKNQTLQNEILGHT
||||||||||||.||||||||||||
Mutant:
GTNLQTVQLFMKRNQTLQNEILGHT"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) SPTB
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay