Immunogenicity 488

summary
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
PATL1
Transcript ID
None
HLA INFO
B*27:02
TCR INFO

No TCR info found!

T cell Tumor cell B*27:02
sequence
Full length protein sequence (770 aa)
MFRYE
1
SLEDC
6
PLDED
11
EDAFQ
16
GLGEE
21
DEEID
26
QFNDD
31
TFGSG
36
AVDDD
41
WQEAH
46
ERLAE
51
LEEKL
56
PVAVN
61
EQTGN
66
GERDE
71
MDLLG
76
DHEEN
81
LAERL
86
SKMVI
91
ENELE
96
DPAIM
101
RAVQT
106
RPVLQ
111
PQPGS
116
LNSSI
121
WDGSE
126
VLRRI
131
RGPLL
136
AQEMP
141
TVSVL
146
EYALP
151
QRPPQ
156
GPEDD
161
RDLSE
166
RALPR
171
RSTSP
176
IIGSP
181
PVRAV
186
PIGTP
191
PKQMA
196
VPSFT
201
QQILC
206
PKPVH
211
VRPPM
216
PPRYP
221
APYGE
226
RMSPN
231
QLCSV
236
PNSSL
241
LGHPF
246
PPSVP
251
PVLSP
256
LQRAQ
261
LLGGA
266
QLQPG
271
RMSPS
276
QFARV
281
PGFVG
286
SPLAA
291
MNPKL
296
LQGRV
301
GQMLP
306
PAPGF
311
RAFFS
316
APPSA
321
TPPPQ
326
QHPPG
331
PGPHL
336
QNLRS
341
QAPMF
346
RPDTT
351
HLHPQ
356
HRRLL
361
HQRQQ
366
QNRSQ
371
HRNLN
376
GAGDR
381
GSHRS
386
SHQDH
391
LRKDP
396
YANLM
401
LQREK
406
DWVSK
411
IQMMQ
416
LQSTD
421
PYLDD
426
FYYQN
431
YFEKL
436
EKLSA
441
AEEIQ
446
GDGPK
451
KERTK
456
LITPQ
461
VAKLE
466
HAYKP
471
VQFEG
476
SLGKL
481
TVSSV
486
NNPRK
491
MIDAV
496
VTSRS
501
EDDET
506
KEKQV
511
RDKRR
516
KTLVI
521
IEKTY
526
SLLLD
531
VEDYE
536
RRYLL
541
SLEEE
546
RPALM
551
DDRKH
556
KICSM
561
YDNLR
566
GKLPG
571
QERPS
576
DDHFV
581
QIMCI
586
RKGKR
591
MVARI
596
LPFLS
601
TEQAA
606
DILMT
611
TARNL
616
PFLIK
621
KDAQD
626
EVLPC
631
LLSPF
636
SLLLY
641
HLPSV
646
SITSL
651
LRQLM
656
NLPQS
661
AATPA
666
LSNPH
671
LTAVL
676
QNKFG
681
LSLLL
686
ILLSR
691
GEDLQ
696
SSDPA
701
TESTQ
706
NNQWT
711
EVMFM
716
ATREL
721
LRIPQ
726
AALAK
731
PISIP
736
TNLVS
741
LFSRY
746
VDRQK
751
LNLLE
756
TKLQL
761
VQGIR
766
Mutation Information
DNA mutation:
None
Peptide Range:
280 ~ 304
Mut AA position:
288 (9 in Wild Type peptide)
Alignment
Wild Type:
"-----SQFARVPGF-----------
||||||||.
Mutant:
GRMSPSQFARVPGYVGSPLAAMNPK"
reference

Nature, 2017

An immunogenic personal neoantigen vaccine for patients with melanoma

Gene Name (from Reference) PATL1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

None

T-cell Source

PBMCs

APC Type

autologous APCs

Assay

IFNg ELISPOT assay