Immunogenicity 4899
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
TP53
Transcript ID
NM_000546
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (393 aa)
MEEPQ
1
SDPSV
6
EPPLS
11
QETFS
16
DLWKL
21
LPENN
26
VLSPL
31
PSQAM
36
DDLML
41
SPDDI
46
EQWFT
51
EDPGP
56
DEAPR
61
MPEAA
66
PPVAP
71
APAAP
76
TPAAP
81
APAPS
86
WPLSS
91
SVPSQ
96
KTYQG
101
SYGFR
106
LGFLH
111
SGTAK
116
SVTCT
121
YSPAL
126
NKMFC
131
QLAKT
136
CPVQL
141
WVDST
146
PPPGT
151
RVRAM
156
AIYKQ
161
SQHMT
166
EVVRR
171
CPHHE
176
RCSDS
181
DGLAP
186
PQHLI
191
RVEGN
196
LRVEY
201
LDDRN
206
TFRHS
211
VVVPY
216
EPPEV
221
GSDCT
226
TIHYN
231
YMCNS
236
SCMGG
241
MNRRP
246
ILTII
251
TLEDS
256
SGNLL
261
GRNSF
266
EVRVC
271
ACPGR
276
DRRTE
281
EENLR
286
KKGEP
291
HHELP
296
PGSTK
301
RALPN
306
NTSSS
311
PQPKK
316
KPLDG
321
EYFTL
326
QIRGR
331
ERFEM
336
FRELN
341
EALEL
346
KDAQA
351
GKEPG
356
GSRAH
361
SSHLK
366
SKKGQ
371
STSRH
376
KKLMF
381
KTEGP
386
DSD
391
Mutation Information
DNA mutation:
None
Peptide Range:
164 ~ 188
Mut AA position:
176 (13 in Wild Type peptide)
Alignment
Wild Type:
"KQSQHMTEVVRRCPHHERCSDSDGL
||||||||||||.||||||||||||
Mutant:
KQSQHMTEVVRRFPHHERCSDSDGL"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) TP53
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay