Immunogenicity 490
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
IDH2
Transcript ID
None
HLA INFO
A*25:01
TCR INFO
No TCR info found!
Full length protein sequence (452 aa)
MAGYL
1
RVVRS
6
LCRAS
11
GSRPA
16
WAPAA
21
LTAPT
26
SQEQP
31
RRHYA
36
DKRIK
41
VAKPV
46
VEMDG
51
DEMTR
56
IIWQF
61
IKEKL
66
ILPHV
71
DIQLK
76
YFDLG
81
LPNRD
86
QTDDQ
91
VTIDS
96
ALATQ
101
KYSVA
106
VKCAT
111
ITPDE
116
ARVEE
121
FKLKK
126
MWKSP
131
NGTIR
136
NILGG
141
TVFRE
146
PIICK
151
NIPRL
156
VPGWT
161
KPITI
166
GRHAH
171
GDQYK
176
ATDFV
181
ADRAG
186
TFKMV
191
FTPKD
196
GSGVK
201
EWEVY
206
NFPAG
211
GVGMG
216
MYNTD
221
ESISG
226
FAHSC
231
FQYAI
236
QKKWP
241
LYMST
246
KNTIL
251
KAYDG
256
RFKDI
261
FQEIF
266
DKHYK
271
TDFDK
276
NKIWY
281
EHRLI
286
DDMVA
291
QVLKS
296
SGGFV
301
WACKN
306
YDGDV
311
QSDIL
316
AQGFG
321
SLGLM
326
TSVLV
331
CPDGK
336
TIEAE
341
AAHGT
346
VTRHY
351
REHQK
356
GRPTS
361
TNPIA
366
SIFAW
371
TRGLE
376
HRGKL
381
DGNQD
386
LIRFA
391
QMLEK
396
VCVET
401
VESGA
406
MTKDL
411
AGCIH
416
GLSNV
421
KLNEH
426
FLNTT
431
DFLDT
436
IKSNL
441
DRALG
446
RQ
451
Mutation Information
DNA mutation:
None
Peptide Range:
184 ~ 211
Mut AA position:
188 (5 in Wild Type peptide)
Alignment
Wild Type:
"--------FVADRAGTF-----------
||||.||||
Mutant:
GDQYKATDFVADWAGTFKMVFTPKDGSG"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) IDH2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay