Immunogenicity 491

summary
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
PDE1C
Transcript ID
None
HLA INFO
A*01:03
TCR INFO

No TCR info found!

T cell Tumor cell A*01:03
sequence
Full length protein sequence (694 aa)
MTDAG
1
NRKEG
6
FKKCR
11
SATFS
16
IDGYS
21
FTIVA
26
NEAGD
31
KNARP
36
LARFS
41
RSKSQ
46
NCLWN
51
SLIDG
56
LTGNV
61
KEKPR
66
PTIVH
71
DPRPP
76
EEILA
81
DELPQ
86
LDSPE
91
VLVKT
96
SFRLR
101
SLVKQ
106
LERGE
111
ASVVD
116
LKKNL
121
EYAAT
126
VLESV
131
YIDET
136
RRLLD
141
TEDEL
146
SDIQS
151
DAVPS
156
EVRDW
161
LASTF
166
TRQMG
171
MMLRR
176
SDEKP
181
RFKSI
186
VHAVQ
191
AGIFV
196
ERMYR
201
RTSNM
206
VGLSY
211
PPAVI
216
EALKD
221
VDKWS
226
FDVFS
231
LNEAS
236
GDHAL
241
KFIFY
246
ELLTR
251
YDLIS
256
RFKIP
261
ISALV
266
SFVEA
271
LEVGY
276
SKHKN
281
PYHNL
286
MHAAD
291
VTQTV
296
HYLLY
301
KTGVA
306
NWLTE
311
LEIFA
316
IIFSA
321
AIHDY
326
EHTGT
331
TNNFH
336
IQTRS
341
DPAIL
346
YNDRS
351
VLENH
356
HLSAA
361
YRLLQ
366
DDEEM
371
NILIN
376
LSKDD
381
WREFR
386
TLVIE
391
MVMAT
396
DMSCH
401
FQQIK
406
AMKTA
411
LQQPE
416
AIEKP
421
KALSL
426
MLHTA
431
DISHP
436
AKAWD
441
LHHRW
446
TMSLL
451
EEFFR
456
QGDRE
461
AELGL
466
PFSPL
471
CDRKS
476
TMVAQ
481
SQVGF
486
IDFIV
491
EPTFT
496
VLTDM
501
TEKIV
506
SPLID
511
ETSQT
516
GGTGQ
521
RRSSL
526
NSISS
531
SDAKR
536
SGVKT
541
SGSEG
546
SAPIN
551
NSVIS
556
VDYKS
561
FKATW
566
TEVVH
571
INRER
576
WRAKV
581
PKEEK
586
AKKEA
591
EEKAR
596
LAAEE
601
QQKEM
606
EAKSQ
611
AEEGA
616
SGKAE
621
KKTSG
626
ETKNQ
631
VNGTR
636
ANKSD
641
NPRGK
646
NSKAE
651
KSSGE
656
QQQNG
661
DFKDG
666
KNKTD
671
KKDHS
676
NIGND
681
SKKTD
686
DSQE
691
Mutation Information
DNA mutation:
None
Peptide Range:
118 ~ 140
Mut AA position:
121 (4 in Wild Type peptide)
Alignment
Wild Type:
"----------VVDLKKNLEY---
|||.||||||
Mutant:
VKQLERGEASVVDFKKNLEYAAT"
reference

Nature, 2017

An immunogenic personal neoantigen vaccine for patients with melanoma

Gene Name (from Reference) PDE1C

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

peptide

T-cell Source

PBMCs

APC Type

autologous APCs

Assay

IFNg ELISPOT assay