Immunogenicity 4920

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
CYP2E1
Transcript ID
NM_000773
HLA INFO
DQA*05:01 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*05:01 DQB*02:02
sequence
Full length protein sequence (493 aa)
MSALG
1
VTVAL
6
LVWAA
11
FLLLV
16
SMWRQ
21
VHSSW
26
NLPPG
31
PFPLP
36
IIGNL
41
FQLEL
46
KNIPK
51
SFTRL
56
AQRFG
61
PVFTL
66
YVGSQ
71
RMVVM
76
HGYKA
81
VKEAL
86
LDYKD
91
EFSGR
96
GDLPA
101
FHAHR
106
DRGII
111
FNNGP
116
TWKDI
121
RRFSL
126
TTLRN
131
YGMGK
136
QGNES
141
RIQRE
146
AHFLL
151
EALRK
156
TQGQP
161
FDPTF
166
LIGCA
171
PCNVI
176
ADILF
181
RKHFD
186
YNDEK
191
FLRLM
196
YLFNE
201
NFHLL
206
STPWL
211
QLYNN
216
FPSFL
221
HYLPG
226
SHRKV
231
IKNVA
236
EVKEY
241
VSERV
246
KEHHQ
251
SLDPN
256
CPRDL
261
TDCLL
266
VEMEK
271
EKHSA
276
ERLYT
281
MDGIT
286
VTVAD
291
LFFAG
296
TETTS
301
TTLRY
306
GLLIL
311
MKYPE
316
IEEKL
321
HEEID
326
RVIGP
331
SRIPA
336
IKDRQ
341
EMPYM
346
DAVVH
351
EIQRF
356
ITLVP
361
SNLPH
366
EATRD
371
TIFRG
376
YLIPK
381
GTVVV
386
PTLDS
391
VLYDN
396
QEFPD
401
PEKFK
406
PEHFL
411
NENGK
416
FKYSD
421
YFKPF
426
STGKR
431
VCAGE
436
GLARM
441
ELFLL
446
LCAIL
451
QHFNL
456
KPLVD
461
PKDID
466
LSPIH
471
IGFGC
476
IPPRY
481
KLCVI
486
PRS
491
Mutation Information
DNA mutation:
None
Peptide Range:
114 ~ 138
Mut AA position:
126 (13 in Wild Type peptide)
Alignment
Wild Type:
"IIFNNGPTWKDIRRFSLTTLRNYGM
||||||||||||.||||||||||||
Mutant:
IIFNNGPTWKDIWRFSLTTLRNYGM"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) CYP2E1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay