Immunogenicity 493
Sample ID
None
Response
Negative
Tumor Type
Melanoma
Gene Symbol
PCDH1
Transcript ID
None
HLA INFO
A*01:01
TCR INFO
No TCR info found!
Full length protein sequence (1060 aa)
MDSGA
1
GGRRC
6
PEAAL
11
LILGP
16
PRMEH
21
LRHSP
26
GPGGQ
31
RLLLP
36
SMLLA
41
LLLLL
46
APSPG
51
HATRV
56
VYKVP
61
EEQPP
66
NTLIG
71
SLAAD
76
YGFPD
81
VGHLY
86
KLEVG
91
APYLR
96
VDGKT
101
GDIFT
106
TETSI
111
DREGL
116
RECQN
121
QLPGD
126
PCILE
131
FEVSI
136
TDLVQ
141
NGSPR
146
LLEGQ
151
IEVQD
156
INDNT
161
PNFAS
166
PVITL
171
AIPEN
176
TNIGS
181
LFPIP
186
LASDR
191
DAGPN
196
GVASY
201
ELQAG
206
PEAQE
211
LFGLQ
216
VAEDQ
221
EEKQP
226
QLIVM
231
GNLDR
236
ERWDS
241
YDLTI
246
KVQDG
251
GSPPR
256
ASSAL
261
LRVTV
266
LDTND
271
NAPKF
276
ERPSY
281
EAELS
286
ENSPI
291
GHSVI
296
QVKAN
301
DSDQG
306
ANAEI
311
EYTFH
316
QAPEV
321
VRRLL
326
RLDRN
331
TGLIT
336
VQGPV
341
DREDL
346
STLRF
351
SVLAK
356
DRGTN
361
PKSAR
366
AQVVV
371
TVKDM
376
NDNAP
381
TIEIR
386
GIGLV
391
THQDG
396
MANIS
401
EDVAE
406
ETAVA
411
LVQVS
416
DRDEG
421
ENAAV
426
TCVVA
431
GDVPF
436
QLRQA
441
SETGS
446
DSKKK
451
YFLQT
456
TTPLD
461
YEKVK
466
DYTIE
471
IVAVD
476
SGNPP
481
LSSTN
486
SLKVQ
491
VVDVN
496
DNAPV
501
FTQSV
506
TEVAF
511
PENNK
516
PGEVI
521
AEITA
526
SDADS
531
GSNAE
536
LVYSL
541
EPEPA
546
AKGLF
551
TISPE
556
TGEIQ
561
VKTSL
566
DREQR
571
ESYEL
576
KVVAA
581
DRGSP
586
SLQGT
591
ATVLV
596
NVLDC
601
NDNDP
606
KFMLS
611
GYNFS
616
VMENM
621
PALSP
626
VGMVT
631
VIDGD
636
KGENA
641
QVQLS
646
VEQDN
651
GDFVI
656
QNGTG
661
TILSS
666
LSFDR
671
EQQST
676
YTFQL
681
KAVDG
686
GVPPR
691
SAYVG
696
VTINV
701
LDEND
706
NAPYI
711
TAPSN
716
TSHKL
721
LTPQT
726
RLGET
731
VSQVA
736
AEDFD
741
SGVNA
746
ELIYS
751
IAGGN
756
PYGLF
761
QIGSH
766
SGAIT
771
LEKEI
776
ERRHH
781
GLHRL
786
VVKVS
791
DRGKP
796
PRYGT
801
ALVHL
806
YVNET
811
LANRT
816
LLETL
821
LGHSL
826
DTPLD
831
IDIAG
836
DPEYE
841
RSKQR
846
GNILF
851
GVVAG
856
VVAVA
861
LLIAL
866
AVLVR
871
YCRQR
876
EAKSG
881
YQAGK
886
KETKD
891
LYAPK
896
PSGKA
901
SKGNK
906
SKGKK
911
SKSPK
916
PVKPV
921
EDEDE
926
AGLQK
931
SLKFN
936
LMSDA
941
PGDSP
946
RIHLP
951
LNYPP
956
GSPDL
961
GRHYR
966
SNSPL
971
PSIQL
976
QPQSP
981
SASKK
986
HQVVQ
991
DLPPA
996
NTFVG
1001
TGDTT
1006
STGSE
1011
QYSDY
1016
SYRTN
1021
PPKYP
1026
SKQVG
1031
QPFQL
1036
STPQP
1041
LPHPY
1046
HGAIW
1051
TEVWE
1056
Mutation Information
DNA mutation:
None
Peptide Range:
569 ~ 592
Mut AA position:
569 (1 in Wild Type peptide)
Alignment
Wild Type:
"----------SLDREQRESY----
.|||||||||
Mutant:
PETGEIQVKTFLDREQRESYELKV"
Nature, 2017
An immunogenic personal neoantigen vaccine for patients with melanomaGene Name (from Reference) PCDH1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
peptide
T-cell
Source
PBMCs
APC
Type
autologous APCs
Assay
IFNg ELISPOT assay