Immunogenicity 4982
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
GLI3
Transcript ID
NM_000168
HLA INFO
C*05:01
TCR INFO
No TCR info found!
Full length protein sequence (1580 aa)
MEAQS
1
HSSTT
6
TEKKK
11
VENSI
16
VKCST
21
RTDVS
26
EKAVA
31
SSTTS
36
NEDES
41
PGQTY
46
HRERR
51
NAITM
56
QPQNV
61
QGLSK
66
VSEEP
71
STSSD
76
ERASL
81
IKKEI
86
HGSLP
91
HVAEP
96
SVPYR
101
GTVFA
106
MDPRN
111
GYMEP
116
HYHPP
121
HLFPA
126
FHPPV
131
PIDAR
136
HHEGR
141
YHYDP
146
SPIPP
151
LHMTS
156
ALSSS
161
PTYPD
166
LPFIR
171
ISPHR
176
NPTAA
181
SESPF
186
SPPHP
191
YINPY
196
MDYIR
201
SLHSS
206
PSLSM
211
ISATR
216
GLSPT
221
DAPHA
226
GVSPA
231
EYYHQ
236
MALLT
241
GQRSP
246
YADII
251
PSAAT
256
AGTGA
261
IHMEY
266
LHAMD
271
STRFS
276
SPRLS
281
ARPSR
286
KRTLS
291
ISPLS
296
DHSFD
301
LQTMI
306
RTSPN
311
SLVTI
316
LNNSR
321
SSSSA
326
SGSYG
331
HLSAS
336
AISPA
341
LSFTY
346
SSAPV
351
SLHMH
356
QQILS
361
RQQSL
366
GSAFG
371
HSPPL
376
IHPAP
381
TFPTQ
386
RPIPG
391
IPTVL
396
NPVQV
401
SSGPS
406
ESSQN
411
KPTSE
416
SAVSS
421
TGDPM
426
HNKRS
431
KIKPD
436
EDLPS
441
PGARG
446
QQEQP
451
EGTTL
456
VKEEG
461
DKDES
466
KQEPE
471
VIYET
476
NCHWE
481
GCARE
486
FDTQE
491
QLVHH
496
INNDH
501
IHGEK
506
KEFVC
511
RWLDC
516
SREQK
521
PFKAQ
526
YMLVV
531
HMRRH
536
TGEKP
541
HKCTF
546
EGCTK
551
AYSRL
556
ENLKT
561
HLRSH
566
TGEKP
571
YVCEH
576
EGCNK
581
AFSNA
586
SDRAK
591
HQNRT
596
HSNEK
601
PYVCK
606
IPGCT
611
KRYTD
616
PSSLR
621
KHVKT
626
VHGPE
631
AHVTK
636
KQRGD
641
IHPRP
646
PPPRD
651
SGSHS
656
QSRSP
661
GRPTQ
666
GALGE
671
QQDLS
676
NTTSK
681
REECL
686
QVKTV
691
KAEKP
696
MTSQP
701
SPGGQ
706
SSCSS
711
QQSPI
716
SNYSN
721
SGLEL
726
PLTDG
731
GSIGD
736
LSAID
741
ETPIM
746
DSTIS
751
TATTA
756
LALQA
761
RRNPA
766
GTKWM
771
EHVKL
776
ERLKQ
781
VNGMF
786
PRLNP
791
ILPPK
796
APAVS
801
PLIGN
806
GTQSN
811
NTCSL
816
GGPMT
821
LLPGR
826
SDLSG
831
VDVTM
836
LNMLN
841
RRDSS
846
ASTIS
851
SAYLS
856
SRRSS
861
GISPC
866
FSSRR
871
SSEAS
876
QAEGR
881
PQNVS
886
VADSY
891
DPIST
896
DASRR
901
SSEAS
906
QSDGL
911
PSLLS
916
LTPAQ
921
QYRLK
926
AKYAA
931
ATGGP
936
PPTPL
941
PNMER
946
MSLKT
951
RLALL
956
GDALE
961
PGVAL
966
PPVHA
971
PRRCS
976
DGGAH
981
GYGRR
986
HLQPH
991
DAPGH
996
GVRRA
1001
SDPVR
1006
TGSEG
1011
LALPR
1016
VPRFS
1021
SLSSC
1026
NPPAM
1031
ATSAE
1036
KRSLV
1041
LQNYT
1046
RPEGG
1051
QSRNF
1056
HSSPC
1061
PPSIT
1066
ENVTL
1071
ESLTM
1076
DADAN
1081
LNDED
1086
FLPDD
1091
VVQYL
1096
NSQNQ
1101
AGYEQ
1106
HFPSA
1111
LPDDS
1116
KVPHG
1121
PGDFD
1126
APGLP
1131
DSHAG
1136
QQFHA
1141
LEQPC
1146
PEGSK
1151
TDLPI
1156
QWNEV
1161
SSGSA
1166
DLSSS
1171
KLKCG
1176
PRPAV
1181
PQTRA
1186
FGFCN
1191
GMVVH
1196
PQNPL
1201
RSGPA
1206
GGYQT
1211
LGENS
1216
NPYGG
1221
PEHLM
1226
LHNSP
1231
GSGTS
1236
GNAFH
1241
EQPCK
1246
APQYG
1251
NCLNR
1256
QPVAP
1261
GALDG
1266
ACGAG
1271
IQASK
1276
LKSTP
1281
MQGSG
1286
GQLNF
1291
GLPVA
1296
PNESA
1301
GSMVN
1306
GMQNQ
1311
DPVGQ
1316
GYLAH
1321
QLLGD
1326
SMQHP
1331
GAGRP
1336
GQQML
1341
GQISA
1346
TSHIN
1351
IYQGP
1356
ESCLP
1361
GAHGM
1366
GSQPS
1371
SLAVV
1376
RGYQP
1381
CASFG
1386
GSRRQ
1391
AMPRD
1396
SLALQ
1401
SGQLS
1406
DTSQT
1411
CRVNG
1416
IKMEM
1421
KGQPH
1426
PLCSN
1431
LQNYS
1436
GQFYD
1441
QTVGF
1446
SQQDT
1451
KAGSF
1456
SISDA
1461
SCLLQ
1466
GTSAK
1471
NSELL
1476
SPGAN
1481
QVTST
1486
VDSLD
1491
SHDLE
1496
GVQID
1501
FDAII
1506
DDGDH
1511
SSLMS
1516
GALSP
1521
SIIQN
1526
LSHSS
1531
SRLTT
1536
PRASL
1541
PFPAL
1546
SMSTT
1551
NMAIG
1556
DMSSL
1561
LTSLA
1566
EESKF
1571
LAVMQ
1576
Mutation Information
DNA mutation:
None
Peptide Range:
1002 ~ 1026
Mut AA position:
1014 (13 in Wild Type peptide)
Alignment
Wild Type:
"VRRASDPVRTGSEGLALPRVPRFSS
||||||||||||.||||||||||||
Mutant:
VRRASDPVRTGSKGLALPRVPRFSS"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) GLI3
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay