Immunogenicity 4993

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
TP53
Transcript ID
NM_001276698
HLA INFO
DQA*02:01 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*02:01 DQB*02:02
sequence
Full length protein sequence (182 aa)
MAIYK
1
QSQHM
6
TEVVR
11
RCPHH
16
ERCSD
21
SDGLA
26
PPQHL
31
IRVEG
36
NLRVE
41
YLDDR
46
NTFRH
51
SVVVP
56
YEPPE
61
VGSDC
66
TTIHY
71
NYMCN
76
SSCMG
81
GMNRR
86
PILTI
91
ITLED
96
SSGNL
101
LGRNS
106
FEVRV
111
CACPG
116
RDRRT
121
EEENL
126
RKKGE
131
PHHEL
136
PPGST
141
KRALP
146
NNTSS
151
SPQPK
156
KKPLD
161
GEYFT
166
LQDQT
171
SFQKE
176
NC
181
Mutation Information
DNA mutation:
None
Peptide Range:
102 ~ 126
Mut AA position:
114 (13 in Wild Type peptide)
Alignment
Wild Type:
"SGNLLGRNSFEVRVCACPGRDRRTE
||||||||||||.||||||||||||
Mutant:
SGNLLGRNSFEVCVCACPGRDRRTE"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) TP53

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay