Immunogenicity 501

Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
IGHV4-28
Transcript ID
ENST00000390612

HLA INFO
DQA*05:01 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*05:01 DQB*02:02
Full length protein sequence (117 aa)
MKHLW
1
FFLLL
6
VAAPR
11
LVLSQ
16
VQLQE
21
SGPGL
26
VKPSD
31
TLSLT
36
CAVSG
41
YSISS
46
SNWWG
51
WIRQP
56
PGKGL
61
EWIGY
66
IYYSG
71
STYYN
76
PSLKS
81
RVTMS
86
VDTSK
91
NQFSL
96
KLSSV
101
TAVDT
106
AVYYC
111
AR
116
Mutation Information
DNA mutation:
None
Peptide Range:
86 ~ 110
Mut AA position:
98 (13 in Wild Type peptide)
Alignment
Wild Type:
"RVTMSVDTSKNQFSLKLSSVTAVDT
||||||||||||.||||||||||||
Mutant:
RVTMSVDTSKNQLSLKLSSVTAVDT"

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ENSG00000211952

Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay