Immunogenicity 5026

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
CHTF18
Transcript ID
NM_022092
HLA INFO
B*40:01
TCR INFO

No TCR info found!

T cell Tumor cell B*40:01
sequence
Full length protein sequence (975 aa)
MEDYE
1
QELCG
6
VEDDF
11
HNQFA
16
AELEV
21
LAELE
26
GASTP
31
SPSGV
36
PLFTA
41
GRPPR
46
TFEEA
51
LARGD
56
AASSP
61
APAAS
66
VGSSQ
71
GGARK
76
RQVDA
81
DLQPA
86
GSLPH
91
APRIK
96
RPRLQ
101
VVKRL
106
NFRSE
111
EMEEP
116
PPPDS
121
SPTDI
126
TPPPS
131
PEDLA
136
ELWGH
141
GVSEA
146
AADVG
151
LTRAS
156
PAARN
161
PVLRR
166
PPILE
171
DYVHV
176
TSTEG
181
VRAYL
186
VLRAD
191
PMAPG
196
VQGSL
201
LHVPW
206
RGGGQ
211
LDLLG
216
VSLAS
221
LKKQV
226
DGERR
231
ERLLQ
236
EAQKL
241
SDTLH
246
SLRSG
251
EEEAA
256
QPLGA
261
PEEEP
266
TDGQD
271
ASSHC
276
LWVDE
281
FAPRH
286
YTELL
291
SDDFT
296
NRCLL
301
KWLKL
306
WDLVV
311
FGHER
316
PSRKP
321
RPSVE
326
PARVS
331
KEATA
336
PGKWK
341
SHEQV
346
LEEML
351
EAGLD
356
PSQRP
361
KQKVA
366
LLCGP
371
PGLGK
376
TTLAH
381
VIARH
386
AGYSV
391
VEMNA
396
SDDRS
401
PEVFR
406
TRIEA
411
ATQME
416
SVLGA
421
GGKPN
426
CLVID
431
EIDGA
436
PVAAI
441
NVLLS
446
ILNRK
451
GPQEV
456
GPQGP
461
AVPSG
466
GGRRR
471
RAEGG
476
LLMRP
481
IICIC
486
NDQFA
491
PSLRQ
496
LKQQA
501
FLLHF
506
PPTLP
511
SRLVQ
516
RLQEV
521
SLRQG
526
MRADP
531
GVLAA
536
LCEKT
541
DNDIR
546
ACINT
551
LQFLY
556
SRGQR
561
ELSVR
566
DVQAT
571
RVGLK
576
DQRRG
581
LFSVW
586
QEVFQ
591
LPRAQ
596
RRRVG
601
QDPAL
606
PADTL
611
LLGDG
616
DAGSL
621
TSASQ
626
RFYRV
631
LHAAA
636
SAGEH
641
EKVVQ
646
GLFDN
651
FLRLR
656
LRDSS
661
LGAVC
666
VALDW
671
LAFDD
676
LLAGA
681
AHHSQ
686
SFQLL
691
RYPPF
696
LPVAF
701
HVLFA
706
SSHTP
711
RITFP
716
SSQQE
721
AQNRM
726
SQMRN
731
LIQTL
736
VSGIA
741
PATRS
746
RATPQ
751
ALLLD
756
ALCLL
761
LDILA
766
PKLRP
771
VSTQL
776
YSTRE
781
KQQLA
786
SLVGT
791
MLAYS
796
LTYRQ
801
ERTPD
806
GQYIY
811
RLEPN
816
VEELC
821
RFPEL
826
PARKP
831
LTYQT
836
KQLIA
841
REIEV
846
EKMRR
851
AEASA
856
RVENS
861
PQVDG
866
SPPGL
871
EGLLG
876
GIGEK
881
GVHRP
886
APRNH
891
EQRLE
896
HIMRR
901
AAREE
906
QPEKD
911
FFGRV
916
VVRST
921
AVPSA
926
GDTAP
931
EQDSV
936
ERRMG
941
TAVGR
946
SEVWF
951
RFNEG
956
VSNAV
961
RRSLY
966
IRDLL
971
Mutation Information
DNA mutation:
None
Peptide Range:
846 ~ 870
Mut AA position:
858 (13 in Wild Type peptide)
Alignment
Wild Type:
"REIEVEKMRRAEASARVENSPQVDG
||||||||||||.||||||||||||
Mutant:
REIEVEKMRRAEVSARVENSPQVDG"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) CHTF18

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay