Immunogenicity 5058

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
PRDM4
Transcript ID
NM_012406
HLA INFO
DRB*15:02
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:02
sequence
Full length protein sequence (801 aa)
MHHRM
1
NEMNL
6
SPVGM
11
EQLTS
16
SSVSN
21
ALPVS
26
GSHLG
31
LAASP
36
THSAI
41
PAPGL
46
PVAIP
51
NLGPS
56
LSSLP
61
SALSL
66
MLPMG
71
IGDRG
76
VMCGL
81
PERNY
86
TLPPP
91
PYPHL
96
ESSYF
101
RTILP
106
GILSY
111
LADRP
116
PPQYI
121
HPNSI
126
NVDGN
131
TALSI
136
TNNPS
141
ALDPY
146
QSNGN
151
VGLEP
156
GIVSI
161
DSRSV
166
NTHGA
171
QSLHP
176
SDGHE
181
VALDT
186
AITME
191
NVSRV
196
TSPIS
201
TDGMA
206
EELTM
211
DGVAG
216
EHSQI
221
PNGSR
226
SHEPL
231
SVDSV
236
SNNLA
241
ADAVG
246
HGGVI
251
PMHGN
256
GLELP
261
VVMET
266
DHIAS
271
RVNGM
276
SDSAL
281
SDSIH
286
TVAMS
291
TNSVS
296
VALST
301
SHNLA
306
SLESV
311
SLHEV
316
GLSLE
321
PVAVS
326
SITQE
331
VAMGT
336
GHVDV
341
SSDSL
346
SFVSP
351
SLQME
356
DSNSN
361
KENMA
366
TLFTI
371
WCTLC
376
DRAYP
381
SDCPE
386
HGPVT
391
FVPDT
396
PIESR
401
ARLSL
406
PKQLV
411
LRQSI
416
VGAEV
421
GVWTG
426
ETIPV
431
RTCFG
436
PLIGQ
441
QSHSM
446
EVAEW
451
TDKAV
456
NHIWK
461
IYHNG
466
VLEFC
471
IITTD
476
ENECN
481
WMMFV
486
RKARN
491
REEQN
496
LVAYP
501
HDGKI
506
FFCTS
511
QDIPP
516
ENELL
521
FYYSR
526
DYAQQ
531
IGVPE
536
HPDVH
541
LCNCG
546
KECNS
551
YTEFK
556
AHLTS
561
HIHNH
566
LPTQG
571
HSGSH
576
GPSHS
581
KERKW
586
KCSMC
591
PQAFI
596
SPSKL
601
HVHFM
606
GHMGM
611
KPHKC
616
DFCSK
621
AFSDP
626
SNLRT
631
HLKIH
636
TGQKN
641
YRCTL
646
CDKSF
651
TQKAH
656
LESHM
661
VIHTG
666
EKNLK
671
CDYCD
676
KLFMR
681
RQDLK
686
QHVLI
691
HTQER
696
QIKCP
701
KCDKL
706
FLRTN
711
HLKKH
716
LNSHE
721
GKRDY
726
VCEKC
731
TKAYL
736
TKYHL
741
TRHLK
746
TCKGP
751
TSSSS
756
APEEE
761
EEDDS
766
EEEDL
771
ADSVG
776
TEDCR
781
INSAV
786
YSADE
791
SLSAH
796
K
801
Mutation Information
DNA mutation:
None
Peptide Range:
635 ~ 659
Mut AA position:
647 (13 in Wild Type peptide)
Alignment
Wild Type:
"THLKIHTGQKNYRCTLCDKSFTQKA
||||||||||||.||||||||||||
Mutant:
THLKIHTGQKNYGCTLCDKSFTQKA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PRDM4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay