Immunogenicity 5127
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
PPP1R3A
Transcript ID
NM_002711
HLA INFO
B*15:01
TCR INFO
No TCR info found!
Full length protein sequence (1122 aa)
MEPSE
1
VPSQI
6
SKDNF
11
LEVPN
16
LSDSL
21
CEDEE
26
VTFQP
31
GFSPQ
36
PSRRG
41
SDSSE
46
DIYLD
51
TPSSG
56
TRRVS
61
FADSF
66
GFNLV
71
SVKEF
76
DCWEL
81
PSAST
86
TFDLG
91
TDIFH
96
TEEYV
101
LAPLF
106
DLPSS
111
KEDLM
116
QQLQI
121
QKAIL
126
ESTES
131
LLGST
136
SIKGI
141
IRVLN
146
VSFEK
151
LVYVR
156
MSLDD
161
WQTHY
166
DILAE
171
YVPNS
176
CDGET
181
DQFSF
186
KIVLV
191
PPYQK
196
DGSKV
201
EFCIR
206
YETSV
211
GTFWS
216
NNNGT
221
NYTFI
226
CQKKE
231
QEPEP
236
VKPWK
241
EVPNR
246
QIKGC
251
LKVKS
256
SKEES
261
SVTSE
266
ENNFE
271
NPKNT
276
DTYIP
281
TIICS
286
HEDKE
291
DLEAS
296
NRNVK
301
DVNRE
306
HDEHN
311
EKELE
316
LMINQ
321
HLIRT
326
RSTAS
331
RDERN
336
TFSTD
341
PVNFP
346
NKAEG
351
LEKKQ
356
IHGEI
361
CTDLF
366
QRSLS
371
PSSSA
376
ESSVK
381
GDFYC
386
NEKYS
391
SGDDC
396
THQPS
401
EETTS
406
NMGEI
411
KPSLG
416
DTSSD
421
ELVQL
426
HTGSK
431
EVLDD
436
NANPA
441
HGNGT
446
VQIPC
451
PSSDQ
456
LMAGN
461
LNKKH
466
EGGAK
471
NIEVK
476
DLGCL
481
RRDFH
486
SDTSA
491
CLKES
496
TEEGS
501
SKEDY
506
YGNGK
511
DDEEQ
516
RIYLG
521
VNEKQ
526
RKNFQ
531
TILHD
536
QERKM
541
GNPKI
546
SVAGI
551
GASNR
556
DLATL
561
LSEHT
566
AIPTR
571
AITAD
576
VSHSP
581
RTNLS
586
WEEAV
591
LTPEH
596
HHLTS
601
EGSAL
606
GGITG
611
QVCSS
616
RTGNV
621
LRNDY
626
LFQVE
631
EKSGG
636
INSED
641
QDNSP
646
QHKQS
651
WNVLE
656
SQGKS
661
RENKT
666
NITEH
671
IKGQT
676
DCEDV
681
WGKRD
686
NTRSL
691
KATTE
696
ELFTC
701
QETVC
706
CELSS
711
LADHG
716
ITEKA
721
EAGTA
726
YIIKT
731
TSEST
736
PESMS
741
AREKA
746
IIAKL
751
PQETA
756
RSDRP
761
IEVKE
766
TAFDP
771
HEGRN
776
DDSHY
781
TLCQR
786
DTVGV
791
IYDND
796
FEKES
801
RLGIC
806
NVRVD
811
EMEKE
816
ETMSM
821
YNPRK
826
THDRE
831
KCGTG
836
NITSV
841
EESSW
846
VITEY
851
QKATS
856
KLDLQ
861
LGMLP
866
TDKTV
871
FSENR
876
DLRQV
881
QELSK
886
KTDSD
891
AIVHS
896
AFNSD
901
TNRAP
906
QNSSP
911
FSKHH
916
TEISV
921
STNEQ
926
AIAVE
931
NAVTT
936
MASQP
941
ISTKS
946
ENICN
951
STREI
956
QGIEK
961
HPYPE
966
SKPEE
971
VSRSS
976
GIVTS
981
GSRKE
986
RCIGQ
991
IFQTE
996
EYSVE
1001
KSLGP
1006
MILIN
1011
KPLEN
1016
MEEAR
1021
HENEG
1026
LVSSG
1031
QSLYT
1036
SGEKE
1041
SDSSA
1046
STSLP
1051
VEESQ
1056
AQGNE
1061
SLFSK
1066
YTNSK
1071
IPYFL
1076
LFLIF
1081
LITVY
1086
HYDLM
1091
IGLTF
1096
YVLSL
1101
SWLSW
1106
EEGRQ
1111
KESVK
1116
KK
1121
Mutation Information
DNA mutation:
None
Peptide Range:
637 ~ 661
Mut AA position:
649 (13 in Wild Type peptide)
Alignment
Wild Type:
"KSGGINSEDQDNSPQHKQSWNVLES
||||||||||||.||||||||||||
Mutant:
KSGGINSEDQDNIPQHKQSWNVLES"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) PPP1R3A
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay