Immunogenicity 5161

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
HOXB8
Transcript ID
NM_024016
HLA INFO
DRB*15:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:01
sequence
Full length protein sequence (243 aa)
MSSYF
1
VNSLF
6
SKYKT
11
GESLR
16
PNYYD
21
CGFAQ
26
DLGGR
31
PTVVY
36
GPSSG
41
GSFQH
46
PSQIQ
51
EFYHG
56
PSSLS
61
TAPYQ
66
QNPCA
71
VACHG
76
DPGNF
81
YGYDP
86
LQRQS
91
LFGAQ
96
DPDLV
101
QYADC
106
KLAAA
111
SGLGE
116
EAEGS
121
EQSPS
126
PTQLF
131
PWMRP
136
QAAAG
141
RRRGR
146
QTYSR
151
YQTLE
156
LEKEF
161
LFNPY
166
LTRKR
171
RIEVS
176
HALGL
181
TERQV
186
KIWFQ
191
NRRMK
196
WKKEN
201
NKDKF
206
PSSKC
211
EQEEL
216
EKQKL
221
ERAPE
226
AADEG
231
DAQKG
236
DKK
241
Mutation Information
DNA mutation:
None
Peptide Range:
42 ~ 66
Mut AA position:
54 (13 in Wild Type peptide)
Alignment
Wild Type:
"PSSGGSFQHPSQIQEFYHGPSSLST
||||||||||||.||||||||||||
Mutant:
PSSGGSFQHPSQTQEFYHGPSSLST"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) HOXB8

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay