Immunogenicity 5183

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
KCNJ4
Transcript ID
NM_004981
HLA INFO
C*06:02
TCR INFO

No TCR info found!

T cell Tumor cell C*06:02
sequence
Full length protein sequence (445 aa)
MHGHS
1
RNGQA
6
HVPRR
11
KRRNR
16
FVKKN
21
GQCNV
26
YFANL
31
SNKSQ
36
RYMAD
41
IFTTC
46
VDTRW
51
RYMLM
56
IFSAA
61
FLVSW
66
LFFGL
71
LFWCI
76
AFFHG
81
DLEAS
86
PGVPA
91
AGGPA
96
AGGGG
101
AAPVA
106
PKPCI
111
MHVNG
116
FLGAF
121
LFSVE
126
TQTTI
131
GYGFR
136
CVTEE
141
CPLAV
146
IAVVV
151
QSIVG
156
CVIDS
161
FMIGT
166
IMAKM
171
ARPKK
176
RAQTL
181
LFSHH
186
AVISV
191
RDGKL
196
CLMWR
201
VGNLR
206
KSHIV
211
EAHVR
216
AQLIK
221
PYMTQ
226
EGEYL
231
PLDQR
236
DLNVG
241
YDIGL
246
DRIFL
251
VSPII
256
IVHEI
261
DEDSP
266
LYGMG
271
KEELE
276
SEDFE
281
IVVIL
286
EGMVE
291
ATAMT
296
TQARS
301
SYLAS
306
EILWG
311
HRFEP
316
VVFEE
321
KSHYK
326
VDYSR
331
FHKTY
336
EVAGT
341
PCCSA
346
RELQE
351
SKITV
356
LPAPP
361
PPPSA
366
FCYEN
371
ELALM
376
SQEEE
381
EMEEE
386
AAAAA
391
AVAAG
396
LGLEA
401
GSKEE
406
AGIIR
411
MLEFG
416
SHLDL
421
ERMQA
426
SLPLD
431
NISYR
436
RESAI
441
Mutation Information
DNA mutation:
None
Peptide Range:
39 ~ 63
Mut AA position:
51 (13 in Wild Type peptide)
Alignment
Wild Type:
"SQRYMADIFTTCVDTRWRYMLMIFS
||||||||||||.||||||||||||
Mutant:
SQRYMADIFTTCMDTRWRYMLMIFS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) KCNJ4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay