Immunogenicity 5185

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
RNF10
Transcript ID
NM_014868
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (811 aa)
MPLSS
1
PNAAA
6
TASDM
11
DKNSG
16
SNSSS
21
ASSGS
26
SKGQQ
31
PPRSA
36
SAGPA
41
GESKP
46
KSDGK
51
NSSGS
56
KRYNR
61
KRELS
66
YPKNE
71
SFNNQ
76
SRRSS
81
SQKSK
86
TFNKM
91
PPQRG
96
GGSSK
101
LFSSS
106
FNGGR
111
RDEVA
116
EAQRA
121
EFSPA
126
QFSGP
131
KKINL
136
NHLLN
141
FTFEP
146
RGQTG
151
HFEGS
156
GHGSW
161
GKRNK
166
WGHKP
171
FNKEL
176
FLQAN
181
CQFVV
186
SEDQD
191
YTAHF
196
ADPDT
201
LVNWD
206
FVEQV
211
RICSH
216
EVPSC
221
PICLY
226
PPTAA
231
KITRC
236
GHIFC
241
WACIL
246
HYLSL
251
SEKTW
256
SKCPI
261
CYSSV
266
HKKDL
271
KSVVA
276
TESHQ
281
YVVGD
286
TITMQ
291
LMKRE
296
KGVLV
301
ALPKS
306
KWMNV
311
DHPIH
316
LGDEQ
321
HSQYS
326
KLLLA
331
SKEQV
336
LHRVV
341
LEEKV
346
ALEQQ
351
LAEEK
356
HTPES
361
CFIEA
366
AIQEL
371
KTREE
376
ALSGL
381
AGSRR
386
EVTGV
391
VAALE
396
QLVLM
401
APLAK
406
ESVFQ
411
PRKGV
416
LEYLS
421
AFDEE
426
TTEVC
431
SLDTP
436
SRPLA
441
LPLVE
446
EEEAV
451
SEPEP
456
EGLPE
461
ACDDL
466
ELADD
471
NLKEG
476
TICTE
481
SSQQE
486
PITKS
491
GFTRL
496
SSSPC
501
YYFYQ
506
AEDGQ
511
HMFLH
516
PVNVR
521
CLVRE
526
YGSLE
531
RSPEK
536
ISATV
541
VEIAG
546
YSMSE
551
DVRQR
556
HRYLS
561
HLPLT
566
CEFSI
571
CELAL
576
QPPVV
581
SKETL
586
EMFSD
591
DIEKR
596
KRQRQ
601
KKARE
606
ERRRE
611
RRIEI
616
EENKK
621
QGKYP
626
EVHIP
631
LENLQ
636
QFPAF
641
NSYTC
646
SSDSA
651
LGPTS
656
TEGHG
661
ALSIS
666
PLSRS
671
PGSHA
676
DFLLT
681
PLSPT
686
ASQGS
691
PSFCV
696
GSLEE
701
DSPFP
706
SFAQM
711
LRVGK
716
AKADV
721
WPKTA
726
PKKDE
731
NSLVP
736
PAPVD
741
SDGES
746
DNSDR
751
VPVPS
756
FQNSF
761
SQAIE
766
AAFMK
771
LDTPA
776
TSDPL
781
SEEKG
786
GKKRK
791
KQKQK
796
LLFST
801
SVVHT
806
K
811
Mutation Information
DNA mutation:
None
Peptide Range:
560 ~ 584
Mut AA position:
572 (13 in Wild Type peptide)
Alignment
Wild Type:
"RHRYLSHLPLTCEFSICELALQPPV
||||||||||||.||||||||||||
Mutant:
RHRYLSHLPLTCKFSICELALQPPV"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) RNF10

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay