Immunogenicity 5205

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
HOXA4
Transcript ID
NM_002141
HLA INFO
C*06:02
TCR INFO

No TCR info found!

T cell Tumor cell C*06:02
sequence
Full length protein sequence (320 aa)
MTMSS
1
FLINS
6
NYIEP
11
KFPPF
16
EEYAQ
21
HSGSG
26
GADGG
31
PGGGP
36
GYQQP
41
PAPPT
46
QHLPL
51
QQPQL
56
PHAGG
61
GREPT
66
ASYYA
71
PRTAR
76
EPAYP
81
AAALY
86
PAHGA
91
ADTAY
96
PYGYR
101
GGASP
106
GRPPQ
111
PEQPP
116
AQAKG
121
PAHGL
126
HASHV
131
LQPQL
136
PPPLQ
141
PRAVP
146
PAAPR
151
RCEAA
156
PATPG
161
VPAGG
166
SAPAC
171
PLLLA
176
DKSPL
181
GLKGK
186
EPVVY
191
PWMKK
196
IHVSA
201
VNPSY
206
NGGEP
211
KRSRT
216
AYTRQ
221
QVLEL
226
EKEFH
231
FNRYL
236
TRRRR
241
IEIAH
246
TLCLS
251
ERQVK
256
IWFQN
261
RRMKW
266
KKDHK
271
LPNTK
276
MRSSN
281
SASAS
286
AGPPG
291
KAQTQ
296
SPHLH
301
PHPHP
306
STSTP
311
VPSSI
316
Mutation Information
DNA mutation:
None
Peptide Range:
128 ~ 152
Mut AA position:
140 (13 in Wild Type peptide)
Alignment
Wild Type:
"HGLHASHVLQPQLPPPLQPRAVPPA
||||||||||||.||||||||||||
Mutant:
HGLHASHVLQPQPPPPLQPRAVPPA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) HOXA4

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay