Immunogenicity 5242

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
ATP6V1C2
Transcript ID
NM_001039362
HLA INFO
DQA*01:02 / DQB*06:01
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:01
sequence
Full length protein sequence (427 aa)
MSEFW
1
LISAP
6
GDKEN
11
LQALE
16
RMNTV
21
TSKSN
26
LSYNT
31
KFAIP
36
DFKVG
41
TLDSL
46
VGLSD
51
ELGKL
56
DTFAE
61
SLIRR
66
MAQSV
71
VEVME
76
DSKGK
81
VQEHL
86
LANGV
91
DLTSF
96
VTHFE
101
WDMAK
106
YPVKQ
111
PLVSV
116
VDTIA
121
KQLAQ
126
IEMDL
131
KSRTA
136
AYNTL
141
KTNLE
146
NLEKK
151
SMGNL
156
FTRTL
161
SDIVS
166
KEDFV
171
LDSEY
176
LVTLL
181
VIVPK
186
PNYSQ
191
WQKTY
196
ESLSD
201
MVVPR
206
STKLI
211
TEDKE
216
GGLFT
221
VTLFR
226
KVIED
231
FKTKA
236
KENKF
241
TVREF
246
YYDEK
251
EIERE
256
REEMA
261
RLLSD
266
KKQQY
271
QTSCV
276
ALKKG
281
SSTFP
286
DHKVK
291
VTPLG
296
NPDRP
301
AAGQT
306
DRERE
311
SEGEG
316
EGPLL
321
RWLKV
326
NFSEA
331
FIAWI
336
HIKAL
341
RVFVE
346
SVLRY
351
GLPVN
356
FQAVL
361
LQPHK
366
KSSTK
371
RLREV
376
LNSVF
381
RHLDE
386
VAATS
391
ILDAS
396
VEIPG
401
LQLNN
406
QDYFP
411
YVYFH
416
IDLSL
421
LD
426
Mutation Information
DNA mutation:
None
Peptide Range:
48 ~ 72
Mut AA position:
60 (13 in Wild Type peptide)
Alignment
Wild Type:
"DSLVGLSDELGKLDTFAESLIRRMA
||||||||||||.||||||||||||
Mutant:
DSLVGLSDELGKRDTFAESLIRRMA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ATP6V1C2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay