Immunogenicity 5263
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
DIAPH1
Transcript ID
NM_001079812
HLA INFO
DRB*15:02
TCR INFO
No TCR info found!
Full length protein sequence (1263 aa)
MEPPG
1
GSLGP
6
GRGTR
11
DKKKG
16
RSPDE
21
LPSAG
26
GDGGK
31
SKKFL
36
ERFTS
41
MRIKK
46
EKEKP
51
NSAHR
56
NSSAS
61
YGDDP
66
TAQSL
71
QDVSD
76
EQVLV
81
LFEQM
86
LLDMN
91
LNEEK
96
QQPLR
101
EKDII
106
IKREM
111
VSQYL
116
YTSKA
121
GMSQK
126
ESSKS
131
AMMYI
136
QELRS
141
GLRDM
146
PLLSC
151
LESLR
156
VSLNN
161
NPVSW
166
VQTFG
171
AEGLA
176
SLLDI
181
LKRLH
186
DEKEE
191
TAGSY
196
DSRNK
201
HEIIR
206
CLKAF
211
MNNKF
216
GIKTM
221
LETEE
226
GILLL
231
VRAMD
236
PAVPN
241
MMIDA
246
AKLLS
251
ALCIL
256
PQPED
261
MNERV
266
LEAMT
271
ERAEM
276
DEVER
281
FQPLL
286
DGLKS
291
GTTIA
296
LKVGC
301
LQLIN
306
ALITP
311
AEELD
316
FRVHI
321
RSELM
326
RLGLH
331
QVLQD
336
LREIE
341
NEDMR
346
VQLNV
351
FDEQG
356
EEDSY
361
DLKGR
366
LDDIR
371
MEMDD
376
FNEVF
381
QILLN
386
TVKDS
391
KAEPH
396
FLSIL
401
QHLLL
406
VRNDY
411
EARPQ
416
YYKLI
421
EECIS
426
QIVLH
431
KNGAD
436
PDFKC
441
RHLQI
446
EIEGL
451
IDQMI
456
DKTKV
461
EKSEA
466
KAAEL
471
EKKLD
476
SELTA
481
RHELQ
486
VEMKK
491
MESDF
496
EQKLQ
501
DLQGE
506
KDALH
511
SEKQQ
516
IATEK
521
QDLEA
526
EVSQL
531
TGEVA
536
KLTKE
541
LEDAK
546
KEMAS
551
LSAAA
556
ITVPP
561
SVPSR
566
APVPP
571
APPLP
576
GDSGT
581
IIPPP
586
PAPGD
591
STTPP
596
PPPPP
601
PPPPP
606
PLPGG
611
VCISS
616
PPSLP
621
GGTAI
626
SPPPP
631
LSGDA
636
TIPPP
641
PPLPE
646
GVGIP
651
SPSSL
656
PGGTA
661
IPPPP
666
PLPGS
671
ARIPP
676
PPPPL
681
PGSAG
686
IPPPP
691
PPLPG
696
EAGMP
701
PPPPP
706
LPGGP
711
GIPPP
716
PPFPG
721
GPGIP
726
PPPPG
731
MGMPP
736
PPPFG
741
FGVPA
746
APVLP
751
FGLTP
756
KKLYK
761
PEVQL
766
RRPNW
771
SKLVA
776
EDLSQ
781
DCFWT
786
KVKED
791
RFENN
796
ELFAK
801
LTLTF
806
SAQTK
811
TSKAK
816
KDQEG
821
GEEKK
826
SVQKK
831
KVKEL
836
KVLDS
841
KTAQN
846
LSIFL
851
GSFRM
856
PYQEI
861
KNVIL
866
EVNEA
871
VLTES
876
MIQNL
881
IKQMP
886
EPEQL
891
KMLSE
896
LKDEY
901
DDLAE
906
SEQFG
911
VVMGT
916
VPRLR
921
PRLNA
926
ILFKL
931
QFSEQ
936
VENIK
941
PEIVS
946
VTAAC
951
EELRK
956
SESFS
961
NLLEI
966
TLLVG
971
NYMNA
976
GSRNA
981
GAFGF
986
NISFL
991
CKLRD
996
TKSTD
1001
QKMTL
1006
LHFLA
1011
ELCEN
1016
DYPDV
1021
LKFPD
1026
ELAHV
1031
EKASR
1036
VSAEN
1041
LQKNL
1046
DQMKK
1051
QISDV
1056
ERDVQ
1061
NFPAA
1066
TDEKD
1071
KFVEK
1076
MTSFV
1081
KDAQE
1086
QYNKL
1091
RMMHS
1096
NMETL
1101
YKELG
1106
EYFLF
1111
DPKKL
1116
SVEEF
1121
FMDLH
1126
NFRNM
1131
FLQAV
1136
KENQK
1141
RRETE
1146
EKMRR
1151
AKLAK
1156
EKAEK
1161
ERLEK
1166
QQKRE
1171
QLIDM
1176
NAEGD
1181
ETGVM
1186
DSLLE
1191
ALQSG
1196
AAFRR
1201
KRGPR
1206
QANRK
1211
AGCAV
1216
TSLLA
1221
SELTK
1226
DDAMA
1231
AVPAK
1236
VSKNS
1241
ETFPT
1246
ILEEA
1251
KELVG
1256
RAS
1261
Mutation Information
DNA mutation:
None
Peptide Range:
1030 ~ 1054
Mut AA position:
1042 (13 in Wild Type peptide)
Alignment
Wild Type:
"DELAHVEKASRVSAENLQKNLDQMK
||||||||||||.||||||||||||
Mutant:
DELAHVEKASRVFAENLQKNLDQMK"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) DIAPH1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay