Immunogenicity 5268

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
LRRN3
Transcript ID
NM_001099660
HLA INFO
A*03:01
TCR INFO

No TCR info found!

T cell Tumor cell A*03:01
sequence
Full length protein sequence (708 aa)
MKDMP
1
LRIHV
6
LLGLA
11
ITTLV
16
QAVDK
21
KVDCP
26
RLCTC
31
EIRPW
36
FTPRS
41
IYMEA
46
STVDC
51
NDLGL
56
LTFPA
61
RLPAN
66
TQILL
71
LQTNN
76
IAKIE
81
YSTDF
86
PVNLT
91
GLDLS
96
QNNLS
101
SVTNI
106
NVKKM
111
PQLLS
116
VYLEE
121
NKLTE
126
LPEKC
131
LSELS
136
NLQEL
141
YINHN
146
LLSTI
151
SPGAF
156
IGLHN
161
LLRLH
166
LNSNR
171
LQMIN
176
SKWFD
181
ALPNL
186
EILMI
191
GENPI
196
IRIKD
201
MNFKP
206
LINLR
211
SLVIA
216
GINLT
221
EIPDN
226
ALVGL
231
ENLES
236
ISFYD
241
NRLIK
246
VPHVA
251
LQKVV
256
NLKFL
261
DLNKN
266
PINRI
271
RRGDF
276
SNMLH
281
LKELG
286
INNMP
291
ELISI
296
DSLAV
301
DNLPD
306
LRKIE
311
ATNNP
316
RLSYI
321
HPNAF
326
FRLPK
331
LESLM
336
LNSNA
341
LSALY
346
HGTIE
351
SLPNL
356
KEISI
361
HSNPI
366
RCDCV
371
IRWMN
376
MNKTN
381
IRFME
386
PDSLF
391
CVDPP
396
EFQGQ
401
NVRQV
406
HFRDM
411
MEICL
416
PLIAP
421
ESFPS
426
NLNVE
431
AGSYV
436
SFHCR
441
ATAEP
446
QPEIY
451
WITPS
456
GQKLL
461
PNTLT
466
DKFYV
471
HSEGT
476
LDING
481
VTPKE
486
GGLYT
491
CIATN
496
LVGAD
501
LKSVM
506
IKVDG
511
SFPQD
516
NNGSL
521
NIKIR
526
DIQAN
531
SVLVS
536
WKASS
541
KILKS
546
SVKWT
551
AFVKT
556
ENSHA
561
AQSAR
566
IPSDV
571
KVYNL
576
THLNP
581
STEYK
586
ICIDI
591
PTIYQ
596
KNRKK
601
CVNVT
606
TKGLH
611
PDQKE
616
YEKNN
621
TTTLM
626
ACLGG
631
LLGII
636
GVICL
641
ISCLS
646
PEMNC
651
DGGHS
656
YVRNY
661
LQKPT
666
FALGE
671
LYPPL
676
INLWE
681
AGKEK
686
STSLK
691
VKATV
696
IGLPT
701
NMS
706
Mutation Information
DNA mutation:
None
Peptide Range:
125 ~ 149
Mut AA position:
137 (13 in Wild Type peptide)
Alignment
Wild Type:
"ENKLTELPEKCLSELSNLQELYINH
||||||||||||.||||||||||||
Mutant:
ENKLTELPEKCLTELSNLQELYINH"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) LRRN3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay