Immunogenicity 5287
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
SLC7A4
Transcript ID
NM_004173
HLA INFO
DQA*02:01 / DQB*02:01
TCR INFO
No TCR info found!
Full length protein sequence (635 aa)
MARGL
1
PTIAS
6
LARLC
11
QKLNR
16
LKPLE
21
DSTME
26
TSLRR
31
CLSTL
36
DLTLL
41
GVGGM
46
VGSGL
51
YVLTG
56
AVAKE
61
VAGPA
66
VLLSF
71
GVAAV
76
ASLLA
81
ALCYA
86
EFGAR
91
VPRTG
96
SAYLF
101
TYVSM
106
GELWA
111
FLIGW
116
NVLLE
121
YIIGG
126
AAVAR
131
AWSGY
136
LDSMF
141
SHSIR
146
NFTET
151
HVGSW
156
QVPLL
161
GHYPD
166
FLAAG
171
IILLA
176
SAFVS
181
CGARV
186
SSWLN
191
HTFSA
196
ISLLV
201
ILFIV
206
ILGFI
211
LAQPH
216
NWSAD
221
EGGFA
226
PFGFS
231
GVMAG
236
TASCF
241
YAFVG
246
FDVIA
251
ASSEE
256
AQNPR
261
RSVPL
266
AIAIS
271
LAIAA
276
GAYIL
281
VSTVL
286
TLMVP
291
WHSLD
296
PDSAL
301
ADAFY
306
QRGYR
311
WAGFI
316
VAAGS
321
ICAMN
326
TVLLS
331
LLFSL
336
PRIVY
341
AMAAD
346
GLFFQ
351
VFAHV
356
HPRTQ
361
VPVAG
366
TLAFG
371
LLTAF
376
LALLL
381
DLESL
386
VQFLS
391
LGTLL
396
AYTFV
401
ATSII
406
VLRFQ
411
KSSPP
416
SSPGP
421
ASPGP
426
LTKQQ
431
SSFSD
436
HLQLV
441
GTVHA
446
SVPEP
451
GELKP
456
ALRPY
461
LGFLD
466
GYSPG
471
AVVTW
476
ALGVM
481
LASAI
486
TIGCV
491
LVFGN
496
STLHL
501
PHWGY
506
ILLLL
511
LTSVM
516
FLLSL
521
LVLGA
526
HQQQY
531
REDLF
536
QIPMV
541
PLIPA
546
LSIVL
551
NICLM
556
LKLSY
561
LTWVR
566
FSIWL
571
LMGLA
576
VYFGY
581
GIRHS
586
KENQR
591
ELPGL
596
NSTHY
601
VVFPR
606
GSLEE
611
TVQAM
616
QPPSQ
621
APAQD
626
PGHME
631
Mutation Information
DNA mutation:
None
Peptide Range:
234 ~ 258
Mut AA position:
246 (13 in Wild Type peptide)
Alignment
Wild Type:
"FSGVMAGTASCFYAFVGFDVIAASS
||||||||||||.||||||||||||
Mutant:
FSGVMAGTASCFCAFVGFDVIAASS"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) SLC7A4
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay