Immunogenicity 5299
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
SKIV2L
Transcript ID
NM_006929
HLA INFO
DRB*15:01
TCR INFO
No TCR info found!
Full length protein sequence (1246 aa)
MMETE
1
RLVLP
6
PPDPL
11
DLPLR
16
AVELG
21
CTGHW
26
ELLNL
31
PGAPE
36
SSLPH
41
GLPPC
46
APDLQ
51
QEAEQ
56
LFLSS
61
PAWLP
66
LHGVE
71
HSARK
76
WQRKT
81
DPWSL
86
LAVLG
91
APVPS
96
DLQAQ
101
RHPTT
106
GQILG
111
YKEVL
116
LENTN
121
LSATT
126
SLSLR
131
RPPGP
136
ASQSL
141
WGNPT
146
QYPFW
151
PGGMD
156
EPTIT
161
DLNTR
166
EEAEE
171
EIDFE
176
KDLLT
181
IPPGF
186
KKGMD
191
FAPKD
196
CPTPA
201
PGLLS
206
LSCML
211
EPLDL
216
GGGDE
221
DENEA
226
VGQPG
231
GPRGD
236
TVSAS
241
PCSAP
246
LARAS
251
SLEDL
256
VLKEA
261
STAVS
266
TPEAP
271
EPPSQ
276
EQWAI
281
PVDAT
286
SPVGD
291
FYRLI
296
PQPAF
301
QWAFE
306
PDVFQ
311
KQAIL
316
HLERH
321
DSVFV
326
AAHTS
331
AGKTV
336
VAEYA
341
IALAQ
346
KHMTR
351
TIYTS
356
PIKAL
361
SNQKF
366
RDFRN
371
TFGDV
376
GLLTG
381
DVQLH
386
PEASC
391
LIMTT
396
EILRS
401
MLYSG
406
SDVIR
411
DLEWV
416
IFDEV
421
HYIND
426
VERGV
431
VWEEV
436
LIMLP
441
DHVSI
446
ILLSA
451
TVPNA
456
LEFAD
461
WIGRL
466
KRRQI
471
YVIST
476
VTRPV
481
PLEHY
486
LFTGN
491
SSKTQ
496
GELFL
501
LLDSR
506
GAFHT
511
KGYYA
516
AVEAK
521
KERMS
526
KHAQT
531
FGAKQ
536
PTHQG
541
GPAQD
546
RGVYL
551
SLLAS
556
LRTRA
561
QLPVV
566
VFTFS
571
RGRCD
576
EQASG
581
LTSLD
586
LTTSS
591
EKSEI
596
HLFLQ
601
RCLAR
606
LRGSD
611
RQLPQ
616
VLHMS
621
ELLNR
626
GLGVH
631
HSGIL
636
PILKE
641
IVEML
646
FSRGL
651
VKVLF
656
ATETF
661
AMGVN
666
MPART
671
VVFDS
676
MRKHD
681
GSTFR
686
DLLPG
691
EYVQM
696
AGRAG
701
RRGLD
706
PTGTV
711
ILLCK
716
GRVPE
721
MADLH
726
RMMMG
731
KPSQL
736
QSQFR
741
LTYTM
746
ILNLL
751
RVDAL
756
RVEDM
761
MKRSF
766
SEFPS
771
RKDSK
776
AHEQA
781
LAELT
786
KRLGA
791
LEEPD
796
MTGQL
801
VDLPE
806
YYSWG
811
EELTE
816
TQHMI
821
QRRIM
826
ESVNG
831
LKSLS
836
AGRVV
841
VVKNQ
846
EHHNA
851
LGVIL
856
QVSSN
861
STSRV
866
FTTLV
871
LCDKP
876
LSQDP
881
QDRGP
886
ATAEV
891
PYPDD
896
LVGFK
901
LFLPE
906
GPCDH
911
TVVKL
916
QPGDM
921
AAITT
926
KVLRV
931
NGEKI
936
LEDFS
941
KRQQP
946
KFKKD
951
PPLAA
956
VTTAV
961
QELLR
966
LAQAH
971
PAGPP
976
TLDPV
981
NDLQL
986
KDMSV
991
VEGGL
996
RARKL
1001
EELIQ
1006
GAQCV
1011
HSPRF
1016
PAQYL
1021
KLRER
1026
MQIQK
1031
EMERL
1036
RFLLS
1041
DQSLL
1046
LLPEY
1051
HQRVE
1056
VLRTL
1061
GYVDE
1066
AGTVK
1071
LAGRV
1076
ACAMS
1081
SHELL
1086
LTELM
1091
FDNAL
1096
STLRP
1101
EEIAA
1106
LLSGL
1111
VCQSP
1116
GDAGD
1121
QLPNT
1126
LKQGI
1131
ERVRA
1136
VAKRI
1141
GEVQV
1146
ACGLN
1151
QTVEE
1156
FVGEL
1161
NFGLV
1166
EVVYE
1171
WARGM
1176
PFSEL
1181
AGLSG
1186
TPEGL
1191
VVRCI
1196
QRLAE
1201
MCRSL
1206
RGAAR
1211
LVGEP
1216
VLGAK
1221
METAA
1226
TLLRR
1231
DIVFA
1236
ASLYT
1241
Q
1246
Mutation Information
DNA mutation:
None
Peptide Range:
641 ~ 665
Mut AA position:
653 (13 in Wild Type peptide)
Alignment
Wild Type:
"PILKEIVEMLFSRGLVKVLFATETF
||||||||||||.||||||||||||
Mutant:
PILKEIVEMLFSHGLVKVLFATETF"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) SKIV2L
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay