Immunogenicity 53
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
MPRIP
Transcript ID
uc002gqy.2
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1188 aa)
MRRGR
1
AEPLA
6
RRERQ
11
AGQAC
16
AAAAA
21
AVAAA
26
PTMSA
31
AKENP
36
CRKFQ
41
ANIFN
46
KSKCQ
51
NCFKP
56
RESHL
61
LNDED
66
LTQAK
71
PIYGG
76
WLLLA
81
PDGTD
86
FDNPV
91
HRSRK
96
WQRRF
101
FILYE
106
HGLLR
111
YALDE
116
MPTTL
121
PQGTI
126
NMNQC
131
TDVVD
136
GEGRT
141
GQKFS
146
LCILT
151
PEKEH
156
FIRAE
161
TKEIV
166
SGWLE
171
MLMVY
176
PRTNK
181
QNQKK
186
KRKVE
191
PPTPQ
196
EPGPA
201
KVAVT
206
SSSSS
211
SSSSS
216
SIPSA
221
EKVPT
226
TKSTL
231
WQEEM
236
RTKDQ
241
PDGSS
246
LSPAQ
251
SPSQS
256
QPPAA
261
SSLRE
266
PGLES
271
KEEES
276
AMSSD
281
RMDCG
286
RKVRV
291
ESGYF
296
SLEKT
301
KQDLK
306
AEEQQ
311
LPPPL
316
SPPSP
321
STPNH
326
RYSCP
331
ESPSQ
336
ELGGP
341
LPSPG
346
PRLPH
351
QMVCS
356
ISLSS
361
LDVAS
366
QPPAY
371
VDSGS
376
TRGRG
381
TERLG
386
SAFAF
391
KASRQ
396
YATLA
401
DVPKA
406
IRISH
411
REAFQ
416
VERRR
421
LERRT
426
RARSP
431
GREEV
436
ARLFG
441
NERRR
446
SQVIE
451
KFEAL
456
DIEKA
461
EHMET
466
NAVGP
471
SPSSD
476
TRQGR
481
SEKRA
486
FPRKR
491
DFTNE
496
APPAP
501
LPDAS
506
ASPLS
511
PHRRA
516
KSLDR
521
RSTEP
526
SVTPD
531
LLNFK
536
KGWLT
541
KQYED
546
GQWKK
551
HWFVL
556
ADQSL
561
RYYRD
566
SVAEE
571
AADLD
576
GEIDL
581
SACYD
586
VTEYP
591
VQRNY
596
GFQIH
601
TKEGE
606
FTLSA
611
MTSGI
616
RRNWI
621
QTIMK
626
HVHPT
631
TAPDV
636
TSSLP
641
EEKNK
646
SSCSF
651
ETCPR
656
PTEKQ
661
EAELG
666
EPDPE
671
QKRSR
676
ARERR
681
REGRS
686
KTFDW
691
AEFRP
696
IQQAL
701
AQERV
706
GGVGP
711
ADTHE
716
PLRPE
721
AEPGE
726
LERER
731
ARRRE
736
ERRKR
741
FGMLD
746
ATDGP
751
GTEDA
756
ALRME
761
VDRSP
766
GLPMS
771
DLKTH
776
NVHVE
781
IEQRW
786
HQVET
791
TPLRE
796
EKQVP
801
IAPVH
806
LSSED
811
GGDRL
816
STHEL
821
TSLLE
826
KELEQ
831
SQKEA
836
SDLLE
841
QNRLL
846
QDQLR
851
VALGR
856
EQSAR
861
EGYVL
866
QATCE
871
RGFAA
876
MEETH
881
QKKIE
886
DLQRQ
891
HQREL
896
EKLRE
901
EKDRL
906
LAEET
911
AATIS
916
AIEAM
921
KNAHR
926
EEMER
931
ELEKS
936
QRSQI
941
SSVNS
946
DVEAL
951
RRQYL
956
EELQS
961
VQREL
966
EVLSE
971
QYSQK
976
CLENA
981
HLAQA
986
LEAER
991
QALRQ
996
CQREN
1001
QELNA
1006
HNQEL
1011
NNRLA
1016
AEITR
1021
LRTLL
1026
TGDGG
1031
GEATG
1036
SPLAQ
1041
GKDAY
1046
ELEVL
1051
LRVKE
1056
SEIQY
1061
LKQEI
1066
SSLKD
1071
ELQTA
1076
LRDKK
1081
YASDK
1086
YKDIY
1091
TELSI
1096
AKAKA
1101
DCDIS
1106
RLKEQ
1111
LKAAT
1116
EALGE
1121
KSPDS
1126
ATVSG
1131
YDIMK
1136
SKSNP
1141
DFLKK
1146
DRSCV
1151
TRQLR
1156
NIRSK
1161
SLKEG
1166
LTVQE
1171
RLKLF
1176
ESRDL
1181
KKD
1186
Mutation Information
DNA mutation:
c.G2928T
Peptide Range:
885 ~ 909
Mut AA position:
None (None in Wild Type peptide)
Alignment
Wild Type:
"HQKKIEDLQRQHQRELEKLREEKDR
||||||||||||.||||||||||||
Mutant:
HQKKIEDLQRQHHRELEKLREEKDR"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) MPRIP
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
HQKKIEDLQRQHHRELEKLREEKDR
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT