Immunogenicity 5306

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
PAX3
Transcript ID
NM_181461
HLA INFO
C*06:02
TCR INFO

No TCR info found!

T cell Tumor cell C*06:02
sequence
Full length protein sequence (403 aa)
MTTLA
1
GAVPR
6
MMRPG
11
PGQNY
16
PRSGF
21
PLEVS
26
TPLGQ
31
GRVNQ
36
LGGVF
41
INGRP
46
LPNHI
51
RHKIV
56
EMAHH
61
GIRPC
66
VISRQ
71
LRVSH
76
GCVSK
81
ILCRY
86
QETGS
91
IRPGA
96
IGGSK
101
PKQVT
106
TPDVE
111
KKIEE
116
YKREN
121
PGMFS
126
WEIRD
131
KLLKD
136
AVCDR
141
NTVPS
146
VSSIS
151
RILRS
156
KFGKG
161
EEEEA
166
DLERK
171
EAEES
176
EKKAK
181
HSIDG
186
ILSER
191
ASAPQ
196
SDEGS
201
DIDSE
206
PDLPL
211
KRKQR
216
RSRTT
221
FTAEQ
226
LEELE
231
RAFER
236
THYPD
241
IYTRE
246
ELAQR
251
AKLTE
256
ARVQV
261
WFSNR
266
RARWR
271
KQAGA
276
NQLMA
281
FNHLI
286
PGGFP
291
PTAMP
296
TLPTY
301
QLSET
306
SYQPT
311
SIPQA
316
VSDPS
321
STVHR
326
PQPLP
331
PSTVH
336
QSTIP
341
SNPDS
346
SSAYC
351
LPSTR
356
HGFSS
361
YTDSF
366
VPPSG
371
PSNPM
376
NPTIG
381
NGLSP
386
QVPFI
391
ISSQI
396
SRK
401
Mutation Information
DNA mutation:
None
Peptide Range:
331 ~ 355
Mut AA position:
343 (13 in Wild Type peptide)
Alignment
Wild Type:
"PQPLPPSTVHQSTIPSNPDSSSAYC
||||||||||||.||||||||||||
Mutant:
PQPLPPSTVHQSMIPSNPDSSSAYC"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PAX3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay