Immunogenicity 5312

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
AGAP5
Transcript ID
NM_001144000
HLA INFO
B*07:02
TCR INFO

No TCR info found!

T cell Tumor cell B*07:02
sequence
Full length protein sequence (686 aa)
MGNIL
1
TCCVH
6
PSVSL
11
EFDQQ
16
QGSVC
21
PSESE
26
IYEAG
31
AGDRM
36
AGAPM
41
AAAVQ
46
PAEVT
51
VEVGE
56
DLHMH
61
HIRDQ
66
EMPEA
71
LEFSL
76
SANPE
81
ASTIF
86
QRNSQ
91
TDALE
96
FNPSA
101
NPEAS
106
TIFQR
111
NSQTD
116
VVEIR
121
RSNCT
126
NHVST
131
ERFSQ
136
QYSSC
141
STIFL
146
DDSTA
151
SQHYL
156
TMTII
161
SVTLE
166
IPHHI
171
TQRDA
176
DRSLS
181
IPDEQ
186
LHSFA
191
VSTVH
196
ITKNR
201
NGGGS
206
LNNYS
211
SSIPS
216
TPSTS
221
QEDPQ
226
FSVPP
231
TANTP
236
TPVCK
241
RSMRW
246
SNLFT
251
SEKGS
256
HPDKE
261
RKAPE
266
NHADT
271
IGSGR
276
AIPIK
281
QGMLL
286
KRSGK
291
WLKTW
296
KKKYV
301
TLCSN
306
GVLTY
311
YSSLG
316
DYMKN
321
IHKKE
326
IDLRT
331
STIKV
336
PGKWP
341
SLATS
346
ACAPI
351
SSSKS
356
NGLSK
361
DMDTG
366
LGDSI
371
CFSPS
376
ISSTT
381
SPKLN
386
PPPSP
391
HANKK
396
KHLKK
401
KSTNN
406
FMIVS
411
ATGQT
416
WHFEA
421
TTYEE
426
RDAWV
431
QAIQS
436
QILAS
441
LQSCE
446
SSKSK
451
SQLTS
456
QSEAM
461
ALQSI
466
QNMRG
471
NAHCV
476
DYETQ
481
NPKWA
486
SLNLG
491
VLMCI
496
ECSGI
501
HRSLG
506
TRLSR
511
VRSLE
516
LDDWP
521
VELRK
526
VMSSI
531
GNDLA
536
NSIWE
541
GSSQG
546
QTKPS
551
VKSTR
556
EEKER
561
WIRSK
566
YEEKL
571
FLAPL
576
PCTEL
581
SLGQH
586
LLRAT
591
ADEDL
596
QTAIL
601
LLAHG
606
SREEV
611
NETCG
616
EGDGC
621
TALHL
626
ACRKG
631
NVVLA
636
QLLIW
641
YGVDV
646
MARDA
651
HGNTA
656
LTYAR
661
QASSQ
666
ECINV
671
LLQYG
676
CPDEC
681
V
686
Mutation Information
DNA mutation:
None
Peptide Range:
23 ~ 51
Mut AA position:
35 (13 in Wild Type peptide)
Alignment
Wild Type:
"SVCPSESEIYEAGAGDRMAGAPMAA----
||||||||||||.||..||||||||
Mutant:
SVCPSESEIYEAAAGYMMAGAPMAAAVQP"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) AGAP5

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay