Immunogenicity 5319

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
CREM
Transcript ID
NM_001267562
HLA INFO
DRB*15:02
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:02
sequence
Full length protein sequence (179 aa)
MAVPT
1
SIYQT
6
STGQY
11
IAIAQ
16
GGTIQ
21
ISNPG
26
SDGVQ
31
GLQAL
36
TMTNS
41
GAPPP
46
GATIV
51
QYAAQ
56
SADGT
61
QQFFV
66
PGSQV
71
VVQAA
76
TGDMP
81
TYQIR
86
APTAA
91
LPQGV
96
VMAAS
101
PGSLH
106
SPQQL
111
AEEAT
116
RKREL
121
RLMKN
126
REAAK
131
ECRRR
136
KKEYV
141
KCLES
146
RVAVL
151
EVQNK
156
KLIEE
161
LETLK
166
DICSP
171
KTDY
176
Mutation Information
DNA mutation:
None
Peptide Range:
121 ~ 145
Mut AA position:
133 (13 in Wild Type peptide)
Alignment
Wild Type:
"RKRELRLMKNREAAKECRRRKKEYV
||||||||||||.||||||||||||
Mutant:
RKRELRLMKNRETAKECRRRKKEYV"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) CREM

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay