Immunogenicity 5329

summary
Sample ID
3978
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
UIMC1
Transcript ID
NM_001199298
HLA INFO
DRB*08:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*08:01
sequence
Full length protein sequence (719 aa)
MPRRK
1
KKVKE
6
VSESR
11
NLEKK
16
DVETT
21
SSVSV
26
KRKRR
31
LEDAF
36
IVISD
41
SDGEE
46
PKEEN
51
GLQKT
56
KTKQS
61
NRAKC
66
LAKRK
71
IAQMT
76
EEEQF
81
ALALK
86
MSEQE
91
AREVN
96
SQEEE
101
EEELL
106
RKAIA
111
ESLNS
116
CRPSD
121
ASATR
126
SRPLA
131
TGPSS
136
QSHQE
141
KTTDS
146
GLTEG
151
IWQLV
156
PPSLF
161
KGSHI
166
SQGNE
171
AEERE
176
EPWDH
181
TEKTE
186
EEPVS
191
GSSGS
196
WDQSS
201
QPVFE
206
NVNVK
211
SFDRC
216
TGHSA
221
EHTQC
226
GKPQE
231
STGRG
236
SAFLK
241
AVQGS
246
GDTSR
251
HCLPT
256
LADAK
261
GLQDT
266
GGTVN
271
YFWGI
276
PFCPD
281
GVDPN
286
QYTKV
291
ILCQL
296
EVYQK
301
SLKMA
306
QRQLL
311
NKKGF
316
GEPVL
321
PRPPS
326
LIQNE
331
CGQGE
336
QASEK
341
NECIS
346
EDMGD
351
EDKEE
356
RQESR
361
ASDWH
366
SKTKD
371
FQESS
376
IKSLK
381
EKLLL
386
EEEPT
391
TSHGQ
396
SSQGI
401
VEETS
406
EEGNS
411
VPASQ
416
SVAAL
421
TSKRS
426
LVLMP
431
ESSAE
436
EITVC
441
PETQL
446
SSSET
451
FDLER
456
EVSPG
461
SRDIL
466
DGVRI
471
IMADK
476
EVGNK
481
EDAEK
486
EVAIS
491
TFSSS
496
NQVSC
501
PLCDQ
506
CFPPT
511
KIERH
516
AMYCN
521
GLMEE
526
DTVLT
531
RRQKE
536
AKTKS
541
DSGTA
546
AQTSL
551
DIDKN
556
EKCYL
561
CKSLV
566
PFREY
571
QCHVD
576
SCLQL
581
AKADQ
586
GDGPE
591
GSGRA
596
CSTVE
601
GKWQQ
606
RLKNP
611
KEKGH
616
SEGRL
621
LSFLE
626
QSEHK
631
TSDAD
636
IKSSE
641
TGAFR
646
VPSPG
651
MEEAG
656
CSREM
661
QSSFT
666
RRDLN
671
ESPVK
676
SFVSI
681
SEATD
686
CLVDF
691
KKQVT
696
VQPGS
701
RTRTK
706
AGRGR
711
RRKF
716
Mutation Information
DNA mutation:
None
Peptide Range:
314 ~ 338
Mut AA position:
326 (13 in Wild Type peptide)
Alignment
Wild Type:
"LLNKKGFGEPVLPRPPSLIQNECGQ
||||||||||||.||||||||||||
Mutant:
LLNKKGFGEPVLRRPPSLIQNECGQ"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) UIMC1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay