Immunogenicity 5334

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
PDLIM5
Transcript ID
NM_001011513
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (487 aa)
MSNYS
1
VSLVG
6
PAPWG
11
FRLQG
16
GKDFN
21
MPLTI
26
SSLKD
31
GGKAA
36
QANVR
41
IGDVV
46
LSIDG
51
INAQG
56
MTHLE
61
AQNKI
66
KGCTG
71
SLNMT
76
LQRAS
81
AAPKP
86
EPVPV
91
QKPTV
96
TSVCS
101
ETSQE
106
LAEGQ
111
RRGSQ
116
GDSKQ
121
QNGPP
126
RKHIV
131
ERYTE
136
FYHVP
141
THSDA
146
SKKRL
151
IEDTE
156
DWRPR
161
TGTTQ
166
SRSFR
171
ILAQI
176
TGTEH
181
LKESE
186
ADNTK
191
KANNS
196
QEPSP
201
QLASS
206
VASTR
211
SMPES
216
LDSPT
221
SGRPG
226
VTSLT
231
TAAAF
236
KPVGS
241
TGVIK
246
SPSWQ
251
RPNQG
256
VPSTG
261
RISNS
266
ATYSG
271
SVAPA
276
NSALG
281
QTQPS
286
DQDTL
291
VQRAE
296
HIPAG
301
KRTPM
306
CAHCN
311
QVIRG
316
PFLVA
321
LGKSW
326
HPEEF
331
NCAHC
336
KNTMA
341
YIGFV
346
EEKGA
351
LYCEL
356
CYEKF
361
FAPEC
366
GRCQR
371
KILGE
376
VISAL
381
KQTWH
386
VSCFV
391
CVACG
396
KPIRN
401
NVFHL
406
EDGEP
411
YCETD
416
YYALF
421
GTICH
426
GCEFP
431
IEAGD
436
MFLEA
441
LGYTW
446
HDTCF
451
VCSVC
456
CESLE
461
GQTFF
466
SKKDK
471
PLCKK
476
HAHSV
481
NF
486
Mutation Information
DNA mutation:
None
Peptide Range:
65 ~ 89
Mut AA position:
77 (13 in Wild Type peptide)
Alignment
Wild Type:
"EAQNKIKGCTGSLNMTLQRASAAPK
||||||||||||.||||||||||||
Mutant:
EAQNKIKGCTGSVNMTLQRASAAPK"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PDLIM5

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay