Immunogenicity 5350

summary
Sample ID
3995
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
PPP2R5B
Transcript ID
NM_006244
HLA INFO
DQA*05:01 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*05:01 DQB*02:02
sequence
Full length protein sequence (497 aa)
METKL
1
PPAST
6
PTSPS
11
SPGLS
16
PVPPP
21
DKVDG
26
FSRRS
31
LRRAR
36
PRRSH
41
SSSQF
46
RYQSN
51
QQELT
56
PLPLL
61
KDVPA
66
SELHE
71
LLSRK
76
LAQCG
81
VMFDF
86
LDCVA
91
DLKGK
96
EVKRA
101
ALNEL
106
VECVG
111
STRGV
116
LIEPV
121
YPDII
126
RMISV
131
NIFRT
136
LPPSE
141
NPEFD
146
PEEDE
151
PNLEP
156
SWPHL
161
QLVYE
166
FFLRF
171
LESPD
176
FQPSV
181
AKRYV
186
DQKFV
191
LMLLE
196
LFDSE
201
DPRER
206
EYLKT
211
ILHRV
216
YGKFL
221
GLRAY
226
IRKQC
231
NHIFL
236
RFIYE
241
FEHFN
246
GVAEL
251
LEILG
256
SIING
261
FALPL
266
KTEHK
271
QFLVR
276
VLIPL
281
HSVKS
286
LSVFH
291
AQLAY
296
CVVQF
301
LEKDA
306
TLTEH
311
VIRGL
316
LKYWP
321
KTCTQ
326
KEVMF
331
LGEME
336
EILDV
341
IEPSQ
346
FVKIQ
351
EPLFK
356
QVARC
361
VSSPH
366
FQVAE
371
RALYF
376
WNNEY
381
ILSLI
386
EDNCH
391
TVLPA
396
VFGTL
401
YQVSK
406
EHWNQ
411
TIVSL
416
IYNVL
421
KTFME
426
MNGKL
431
FDELT
436
ASYKL
441
EKQQE
446
QQKAQ
451
ERQEL
456
WQGLE
461
ELRLR
466
RLQGT
471
QGAKE
476
APLQR
481
LTPQV
486
AASGG
491
QS
496
Mutation Information
DNA mutation:
None
Peptide Range:
1 ~ 24
Mut AA position:
12 (12 in Wild Type peptide)
Alignment
Wild Type:
"METKLPPASTPTSPSSPGLSPVPPP
|||||||||||.||||||||||||
Mutant:
METKLPPASTPPSPSSPGLSPVPP-"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PPP2R5B

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay