Immunogenicity 5360

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
NPDC1
Transcript ID
NM_015392
HLA INFO
A*25:01
TCR INFO

No TCR info found!

T cell Tumor cell A*25:01
sequence
Full length protein sequence (325 aa)
MATPL
1
PPPSP
6
RHLRL
11
LRLLL
16
SGLVL
21
GAALR
26
GAAAG
31
HPDVA
36
ACPGS
41
LDCAL
46
KRRAR
51
CPPGA
56
HACGP
61
CLQPF
66
QEDQQ
71
GLCVP
76
RMRRP
81
PGGGR
86
PQPRL
91
EDEID
96
FLAQE
101
LARKE
106
SGHST
111
PPLPK
116
DRQRL
121
PEPAT
126
LGFSA
131
RGQGL
136
ELGLP
141
STPGT
146
PTPTP
151
HTSLG
156
SPVSS
161
DPVHM
166
SPLEP
171
RGGQG
176
DGLAL
181
VLILA
186
FCVAG
191
AAALS
196
VASLC
201
WCRLQ
206
REIRL
211
TQKAD
216
YATAK
221
APGSP
226
AAPRI
231
SPGDQ
236
RLAQS
241
AEMYH
246
YQHQR
251
QQMLC
256
LERHK
261
EPPKE
266
LDTAS
271
SDEEN
276
EDGDF
281
TVYEC
286
PGLAP
291
TGEME
296
VRNPL
301
FDHAA
306
LSAPL
311
PAPSS
316
PPALP
321
Mutation Information
DNA mutation:
None
Peptide Range:
40 ~ 64
Mut AA position:
52 (13 in Wild Type peptide)
Alignment
Wild Type:
"AACPGSLDCALKRRARCPPGAHACG
||||||||||||.||||||||||||
Mutant:
AACPGSLDCALKSRARCPPGAHACG"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) NPDC1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay