Immunogenicity 5374
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
INPP5K
Transcript ID
NM_001135642
HLA INFO
B*07:02
TCR INFO
No TCR info found!
Full length protein sequence (372 aa)
MDVLS
1
PLSFI
6
KVSHV
11
RMQGI
16
LLLVF
21
AKYQH
26
LPYIQ
31
ILSTK
36
STPTG
41
LFGYW
46
GNKGG
51
VNICL
56
KLYGY
61
YVSII
66
NCHLP
71
PHISN
76
NYQRL
81
EHFDR
86
ILEMQ
91
NCEGR
96
DIPNI
101
LDHDL
106
IIWFG
111
DMNFR
116
IEDFG
121
LHFVR
126
ESIKN
131
RCYGG
136
LWEKD
141
QLSIA
146
KKHDP
151
LLREF
156
QEGRL
161
LFPPT
166
YKFDR
171
NSNDY
176
DTSEK
181
KRKPA
186
WTDRI
191
LWRLK
196
RQPCA
201
GPDTP
206
IPPAS
211
HFSLS
216
LRGYS
221
SHMTY
226
GISDH
231
KPVSG
236
TFDLE
241
LKPLV
246
SAPLI
251
VLMPE
256
DLWTV
261
ENDMM
266
VSYSS
271
TSDFP
276
SSPWD
281
WIGLY
286
KVGLR
291
DVNDY
296
VSYAW
301
VGDSK
306
VSCSD
311
NLNQV
316
YIDIS
321
NIPTT
326
EDEFL
331
LCYYS
336
NSLRS
341
VVGIS
346
RPFQI
351
PPGSL
356
REDPL
361
GEAQP
366
QI
371
Mutation Information
DNA mutation:
None
Peptide Range:
189 ~ 213
Mut AA position:
201 (13 in Wild Type peptide)
Alignment
Wild Type:
"PAWTDRILWRLKRQPCAGPDTPIPP
||||||||||||.||||||||||||
Mutant:
PAWTDRILWRLKQQPCAGPDTPIPP"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) INPP5K
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay